Safi Hazim J
Baylor College of Medicine, The Methodist Hospital, Houston, Texas, U.S.A.
Artif Organs. 1996 May;20(5):694-699. doi: 10.1111/j.1525-1594.1996.tb04505.x.
We reviewed the role of the BioMedicus pump in the reduction of neurologic complications following the repair of Type 1 and Type 2 thoracoabdominal aortic aneurysms. Since 1991, we have used several different methods for the repair of thoracoabdominal aortic aneurysms including simple cross-clamping, selective use of the BioMedicus pump, cardiopulmonary bypass with or without profound hypothermia, and most recently, distal aortic perfusion using the BioMedicus pump combined with cerebral spinal fluid drainage. This latter method has been the most promising in rectifying the side effects of aortic clamping and in providing the time necessary for thorough thoracoabdominal aortic aneurysm repair. On our service, the ongoing study of the BioMedicus pump and distal aortic perfusion in conjunction with cerebral spinal fluid drainage has shown that these adjuncts can extend the tolerance of the spinal cord to ischemia and lower the overall rate of neurologic complications for Type 1 and Type 2 thoracoabdominal aortic aneurysm repairs to a rate of 5% (early results) and 3% (late results). We highly recommend distal aortic perfusion using the BioMedicus pump combined with cerebral spinal fluid drainage for thoracoabdominal aortic aneurysm repair.
我们回顾了BioMedicus泵在降低1型和2型胸腹主动脉瘤修复术后神经并发症方面的作用。自1991年以来，我们采用了几种不同的方法来修复胸腹主动脉瘤，包括单纯交叉钳夹、选择性使用BioMedicus泵、有或无深度低温的体外循环，以及最近使用BioMedicus泵结合脑脊液引流进行远端主动脉灌注。后一种方法在纠正主动脉钳夹的副作用以及为彻底修复胸腹主动脉瘤提供必要时间方面最具前景。在我们的医疗服务中，对BioMedicus泵和远端主动脉灌注结合脑脊液引流的持续研究表明，这些辅助措施可以延长脊髓对缺血的耐受性，并将1型和2型胸腹主动脉瘤修复术后神经并发症的总体发生率降低至5%（早期结果）和3%（晚期结果）。我们强烈推荐使用BioMedicus泵结合脑脊液引流进行远端主动脉灌注来修复胸腹主动脉瘤。
