Shomura Yu, Shimono Takatsugu, Onoda Koji, Hioki Iwao, Tenpaku Hironori, Maze Yasumi, Mizumoto Torn, Tani Kazuhiro, Tanaka Kuniyoshi, Shimpo Hideto, Yuasa Hiroshi, Yada Isao
Department of Thoracic and Cardiovascular Surgery, Mie University School of Medicine, Mie, Japan.
Artif Organs. 1996 May;20(5):711-714. doi: 10.1111/j.1525-1594.1996.tb04509.x.
The Nikkiso HPM-15 is a minimally sized centrifugal pump. Preliminary results regarding clinical use of this pump for cardiopulmonary bypass (CPB) procedures have been reported previously. Recently, we have managed some additional cases using a newly developed controller. This article reports our clinical experiences with the use of this pump. We have managed 23 cases with a Nikkiso centrifugal pump. Twenty-two patients underwent CPB and 1 patient with fulminant viral myocarditis underwent percutaneous cardiopulmonary support (PCPS). With this pump, the circuit was extremely easy to prepare and deaeration was achieved readily. Hemodynamics during CPB and PCPS were stable in all cases. The increase in serum-free hemoglobin levels during CPB with this pump was as low as that seen in preliminary tests. A decrease in the platelet count was observed after the initiation of CPB with this pump; however, platelet counts returned to preoperative values 7 days after surgery. Moreover, urine output during CPB with this pump was as high as that seen in preliminary tests. No abnormalities in renal or liver function occurred during CPB. It appears that this new centrifugal pump is safe and easy to operate, and we conclude that it is useful for CPB and PCPS.
日机装HPM - 15是一款尺寸极小的离心泵。此前已有关于该泵用于体外循环（CPB）手术临床应用的初步结果报道。最近，我们使用新开发的控制器处理了一些额外的病例。本文报告了我们使用该泵的临床经验。我们使用日机装离心泵处理了23例病例。22例患者接受了体外循环，1例暴发性病毒性心肌炎患者接受了经皮心肺支持（PCPS）。使用该泵时，回路极易准备，且能轻松实现排气。所有病例在体外循环和经皮心肺支持期间的血流动力学均稳定。使用该泵进行体外循环期间血清游离血红蛋白水平的升高与初步试验所见一样低。使用该泵开始体外循环后观察到血小板计数下降；然而，术后7天血小板计数恢复到术前值。此外，使用该泵进行体外循环期间的尿量与初步试验所见一样高。体外循环期间未出现肾或肝功能异常。看来这款新型离心泵安全且易于操作，我们得出结论，它对体外循环和经皮心肺支持有用。
