Steele Kelsy R, Szczotka-Flynn Loretta
The Ohio State University College of Optometry, Columbus, Ohio, USA.
University Hospitals Eye Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Clin Exp Optom. 2017 Sep;100(5):473-481. doi: 10.1111/cxo.12598. Epub 2017 Sep 4.
Corneal infiltrative events (CIEs) are well established as a risk associated with soft contact lens wear. The incidence of symptomatic CIEs during extended soft lens wear ranges from 2.5 to six per cent; when asymptomatic CIEs are included, the incidence can be as high as 20-25 per cent. In daily soft lens wear, the annual incidence of symptomatic CIEs is about three per cent. There are various accepted methods of categorising CIEs, and a scoring system based on clinical signs and symptoms is a good approach to grade severity. Lens-related risk factors include extended wear, silicone hydrogel material, the use of multipurpose solutions, bacterial bioburden and reusable lenses. Recent studies report that daily disposable lenses reduce the risk of CIEs.
角膜浸润事件（CIEs）已被确认为与软性隐形眼镜佩戴相关的一种风险。在长时间佩戴软性隐形眼镜期间，有症状的CIEs发生率为2.5%至6%；若包括无症状的CIEs，发生率可高达20% - 25%。在日常佩戴软性隐形眼镜时，有症状的CIEs年发生率约为3%。有多种公认的CIEs分类方法，基于临床体征和症状的评分系统是分级严重程度的一种好方法。与镜片相关的风险因素包括长时间佩戴、硅水凝胶材料、使用多功能护理液、细菌生物负荷和可重复使用的镜片。最近的研究报告称，日抛型隐形眼镜可降低CIEs的风险。
