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门诊柔性输尿管镜治疗尿路结石的安全性与可行性:一项单中心回顾性研究

[Safety and feasibility of outpatient flexible ureteroscopy for urinary stones: A retrospective single-center study].

作者信息

Bosquet E, Peyronnet B, Mathieu R, Khene Z-E, Pradere B, Manunta A, Vincendeau S, Guille F, Bensalah K, Verhoest G

机构信息

Service d'urologie, CHU de Rennes, 35000 Rennes, France.

Service d'urologie, CHU de Rennes, 35000 Rennes, France.

出版信息

Prog Urol. 2017 Dec;27(16):1043-1049. doi: 10.1016/j.purol.2017.07.246. Epub 2017 Aug 30.

Abstract

AIM

Management of urolithiasis has changed over the past decades. Outpatient surgery has become a major issue for healthcare systems. The aim of this study was to assess the feasibility of outpatient flexible ureteroscopy.

METHODS

A single-center retrospective study has been conducted including all patients who underwent an outpatient flexible ureteroscopy between January 2012 and December 2013. Failure of outpatient management was defined as length of hospital stay>12 hours or readmission within 48 hours after discharge. Univariate analysis was performed to seek for predictors of failure of outpatient management.

RESULTS

One hundred and fifty-seven patients who underwent a total of 174 procedures were included. They were mostly men (57.5 %), with a mean body mass index of 25.2kg/m (±4.3). The stones were mostly unique (64.3 %), with a mean size of 14.2mm (±11.2). Eighty patients had a double J stent preoperatively (46.5 %), and mean operative time was 64.2 minutes (±34.1). An ureteral access sheath was used in 39 procedures (22.4 %). A double J stent was left postoperatively in 103 patients (59.1 %). In total, 165 procedures (94.8 %) were performed successfully as outpatient surgery. On postoperative imaging, the stone-free rate was 69.5 %. Postoperative complications occurred in 3.4 % of cases and were mostly minor (i.e. Clavien 1-2; 83.3 %). Predictive factors of failed outpatient management were male gender (P=0.04), BMI (P=0.03), and anticoagulants intake (P=0.003).

CONCLUSION

Outpatient flexible ureteroscopy for urinary stones is feasible and its low failure and complications rate may allow a wider spread of its use.

LEVEL OF EVIDENCE

摘要

目的

在过去几十年中,尿石症的治疗方式发生了变化。门诊手术已成为医疗系统的一个重要问题。本研究的目的是评估门诊软性输尿管镜检查的可行性。

方法

进行了一项单中心回顾性研究,纳入了2012年1月至2013年12月期间接受门诊软性输尿管镜检查的所有患者。门诊治疗失败定义为住院时间>12小时或出院后48小时内再次入院。进行单因素分析以寻找门诊治疗失败的预测因素。

结果

共纳入157例患者,他们总共接受了174次手术。患者大多为男性(57.5%),平均体重指数为25.2kg/m(±4.3)。结石大多为单发(64.3%),平均大小为14.2mm(±11.2)。80例患者术前放置了双J支架(46.5%),平均手术时间为64.2分钟(±34.1)。39例手术(22.4%)使用了输尿管鞘。103例患者术后留置了双J支架(59.1%)。总共165例手术(94.8%)作为门诊手术成功完成。术后影像学检查显示,结石清除率为69.5%。3.4%的病例发生了术后并发症,且大多为轻微并发症(即Clavien 1-2级;83.3%)。门诊治疗失败的预测因素为男性(P=0.04)、体重指数(P=0.03)和抗凝剂使用情况(P=0.003)。

结论

门诊软性输尿管镜治疗尿路结石是可行的,其低失败率和并发症发生率可能使其应用得到更广泛推广。

证据级别

4级。

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