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日间输尿管镜检查(DC-URS)治疗结石病的结果:4.5 年以上的前瞻性结果。

Results of day-case ureterorenoscopy (DC-URS) for stone disease: prospective outcomes over 4.5 years.

机构信息

Department of Urology, University Hospital Southampton NHS Trust, Southampton, SO16 6YD, UK.

Department of Anaesthetics, University Hospital Southampton NHS Trust, Southampton, SO16 6YD, UK.

出版信息

World J Urol. 2017 Nov;35(11):1757-1764. doi: 10.1007/s00345-017-2061-1. Epub 2017 Jun 15.

Abstract

PURPOSE

To investigate the prospective outcomes of day-case ureterorenoscopy (DC-URS) for stone disease. With the rising prevalence of stone disease in the face of finite resources, there is increasing pressure to undertake procedures as a day case avoiding in-patient stay. There are a limited number of studies reporting on the feasibility of ureteroscopy as a day-case procedure. This study aimed to investigate the prospective outcomes and predictors precluding to DC-URS for stone disease in patients treated in our university teaching hospital.

MATERIALS AND METHODS

Between March 2012 and July 2016, consecutive cases of adult stone ureteroscopy performed or supervised by a single surgeon were recorded in a prospective database. Patients underwent pre-operative counselling in a specialist stone clinic and were admitted to a dedicated 'Surgical day unit' on the day of surgery. A standardised anaesthetic protocol was adhered to in all cases. Data on patient demographics, stone parameters, pre-operative assessment, operative details, length of stay, stone-free rate and complication rates were collected and analysed.

RESULTS

A total of 544 consecutive adult ureteroscopy for stone disease were conducted over the study period with a day-case rate of 77.7%. Thirty-nine percent of failed day-case ureteroscopy were due to late completion of ureteroscopy and due to associated social circumstances of patients. The mean stone size, operating time duration and post-operative stent insertion rates for DC-URS patients were 14 mm, 46 min and 96.5%, respectively. Post-operatively, the mean stone-free rate (SFR), unplanned re-admissions and complications for DC-URS patients were 95, 4 and 4%, respectively. A higher failure of DC-URS was related to patient's age (p = 0.003), positive pre-operative urine culture (p < 0.001), elevated pre-operative serum creatinine (p < 0.001) and higher mean operating time (p < 0.02).

CONCLUSION

Based on our results, a day-case ureteroscopy rate of nearly 78% can be achieved. With its acceptable complication rate, and low re-admission rates, DC-URS is a safe and feasible option in a majority of patients with stone disease.

摘要

目的

探讨日间输尿管镜碎石术(DC-URS)治疗结石病的前瞻性结果。面对有限的资源,结石病的发病率不断上升,因此越来越需要开展日间手术,避免住院。目前,仅有少数研究报告了输尿管镜作为日间手术的可行性。本研究旨在调查我们大学教学医院治疗的结石病患者中,DC-URS 的可行性和预测因素。

材料与方法

2012 年 3 月至 2016 年 7 月,连续记录由一位外科医生进行或监督的成人输尿管镜碎石术病例,将这些病例纳入前瞻性数据库。患者在结石病专科门诊进行术前咨询,并在手术当天入住专门的“手术日间病房”。所有病例均采用标准化的麻醉方案。收集并分析患者人口统计学、结石参数、术前评估、手术细节、住院时间、结石清除率和并发症发生率等数据。

结果

研究期间共进行了 544 例连续的成人输尿管镜碎石术,日间手术率为 77.7%。39%的日间手术失败是由于输尿管镜检查延迟完成以及患者的社会环境所致。DC-URS 患者的平均结石大小、手术时间和术后支架置入率分别为 14mm、46 分钟和 96.5%。术后,DC-URS 患者的平均结石清除率(SFR)、非计划再入院率和并发症发生率分别为 95%、4%和 4%。DC-URS 失败与患者年龄(p=0.003)、术前尿培养阳性(p<0.001)、术前血清肌酐升高(p<0.001)和平均手术时间较长(p<0.02)有关。

结论

根据我们的结果,近 78%的患者可以实现日间输尿管镜碎石术。DC-URS 具有可接受的并发症发生率和较低的再入院率,是大多数结石病患者安全可行的选择。

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