Le Hai H, Salas Rachel Marie E, Gamaldo Alyssa, Billups Kevin L, Dziedzic Peter, Choi Seulah, Bermudez Neftali, Thorpe Roland J, Gamaldo Charlene E
Department of Neurology, Johns Hopkins Medicine, Baltimore, MD, USA.
Human Development and Family Studies, Penn State University, University Park, PA, USA.
Int J Clin Pract. 2018 Jan;72(1). doi: 10.1111/ijcp.12999. Epub 2017 Sep 4.
Evidence linking sleep disruption and sexual dysfunction in men is mounting; yet the characterisation of sleep patterns and complaints utilising a clinically feasible method within this patient population remain largely under-reported.
A pilot study aiming to demonstrate a clinically feasible method to characterise the sleep patterns and complaints in a representative sample of patients treated in a men's health clinic.
Male patients (n = 48) completed a battery of validated sleep questionnaires using an mHealth mobile platform, MySleepScript, at the Johns Hopkins Men's Health and Vitality Center. Metrics related to clinical feasibility such as completion time, ease of use, preference of electronic format, and patient satisfaction were also collected.
Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), Berlin Questionnaire, Patient Health Questionnaire (PHQ-9), and Primary Care PTSD Screen (PC-PTSD).
Primary urological chief symptoms for this sample patient population were erectile dysfunction (ED; 80%), hypogonadism (40%), benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS; 40%) and Peyronie's disease (10%). Mean PSQI score was 7.8 [SD 4.2], with 67% of all patients falling within the "poor sleeper" range. At least mild symptoms of depression were noted in 40% and 43% were at risk for obstructive sleep apnea (OSA) on the Berlin Questionnaire.
This pilot study demonstrated the feasibility and potential utility of an mHealth platform to assist clinicians, within a men's health clinic, in detecting sleep disturbances. Disrupted sleep was revealed in well over half of this sample of patients. As a result of the growing evidence linking poor sleep and sleep disorders (eg, OSA) to the conditions relevant to men's health (eg, erectile dysfunction, hypogonadism and BPH), further efforts beyond this pilot study are necessary to identify the aetiological processes underlying the association between specific disrupted sleep disorders and urological conditions.
越来越多的证据表明男性睡眠中断与性功能障碍之间存在关联；然而，在这一患者群体中，使用临床可行的方法对睡眠模式和相关主诉进行描述的情况仍大多未得到充分报道。
开展一项试点研究，旨在证明一种临床可行的方法，用于描述在男性健康诊所接受治疗的代表性患者样本的睡眠模式和相关主诉。
48名男性患者在约翰霍普金斯男性健康与活力中心使用移动健康（mHealth）移动平台MySleepScript完成了一系列经过验证的睡眠问卷。还收集了与临床可行性相关的指标，如完成时间、易用性、对电子格式的偏好以及患者满意度。
匹兹堡睡眠质量指数（PSQI）、失眠严重程度指数（ISI）、柏林问卷、患者健康问卷（PHQ - 9）和初级保健创伤后应激障碍筛查量表（PC - PTSD）。
该样本患者群体的主要泌尿外科主要症状为勃起功能障碍（ED；80%）、性腺功能减退（40%）、良性前列腺增生/下尿路症状（BPH/LUTS；40%）和佩罗尼氏病（10%）。PSQI平均得分为7.8[标准差4.2]，所有患者中有67%属于“睡眠不佳者”范围。根据柏林问卷，40%的患者至少有轻度抑郁症状，43%的患者有阻塞性睡眠呼吸暂停（OSA）风险。
这项试点研究证明了mHealth平台在男性健康诊所协助临床医生检测睡眠障碍方面的可行性和潜在效用。在该患者样本中，超过一半的人存在睡眠中断情况。由于越来越多的证据表明睡眠不佳和睡眠障碍（如OSA）与男性健康相关疾病（如勃起功能障碍、性腺功能减退和BPH）之间存在关联，因此除了这项试点研究之外，还需要进一步努力来确定特定睡眠障碍与泌尿外科疾病之间关联的潜在病因机制。
