Sasmaz Ahmet, Ozkan Suheyla, Gursu Mehmet Ferit, Sasmaz Merve
Fırat University, Department of Geological Engineering 23119 Elazig, Turkey.
Fırat University, Department of Geological Engineering 23119 Elazig, Turkey.
Appl Radiat Isot. 2017 Nov;129:185-188. doi: 10.1016/j.apradiso.2017.07.060. Epub 2017 Jul 31.
The present study was to investigate the alteration of biochemical and hematological parameters on the rats exposed to natural radiation caused by britholite mineral (REE, Ca, Na) (Si,P)O within 15 days. Britholite was collected from Kuluncak mining area, Malatya, bearing radioactive Th isotope (average 2.68% ThO), which is rare earth elements found high amounts. Britholite is toxic for the living animal and human and emits the radiation to natural surroundings about 0.8R/h due to its radioactive Th properties. In this study, animals were divided to two groups, one groups exposed to Th, the other group was served as control group. All animals were fed with same food and water during the experimental study (15 days). After 15 days, the hematologic and biochemical parameters (Na, K, Ca, P, Cl, Mg, glucose, cholesterol, HDL, LDL, albumin, Uric acid, AST, ALT, total protein, Fe, urea and creatine level and hormonal parameters (TSH, T3 and T4)) were analyzed The levels of serum triglyceride in the ionizing radiation group generated by Th isotope (p < 0.05) statistically significantly increased compared with control group value. Lymphocytes, TSH, T3 and T4 decreased in the ionizing radiation group generated by Th isotope while neutrophils increased in the ionizing radiation group generated by Th isotope. The rats exposed to ionizing radiation generated by Th isotope caused significant changes in the hematological and biochemical parameters and the most significantly alteration was observed in the thyroid hormonal levels, which might be due to high radiation doses within short time. These results should be kept in mind to maintain healthy life in people who lives in britholite mineral vicinity.
