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麻醉性腰椎注射对慢性下腰痛患者步态时空参数的急性影响:一项初步研究。

Acute effects of anesthetic lumbar spine injections on temporal spatial parameters of gait in individuals with chronic low back pain: A pilot study.

作者信息

Herndon Carl L, Horodyski MaryBeth, Vincent Heather K

机构信息

Department of Orthopaedic Surgery at Columbia University Medical Center/New York-Presbyterian Hospital, 622 W 168th Street, PH11, New York, NY, 10032, USA.

Department of Orthopaedics and Rehabilitation, Division of Research, Interdisciplinary Center for Musculoskeletal Training and Research, University of Florida, PO Box 112727, Gainesville, FL, 32611, USA.

出版信息

Gait Posture. 2017 Oct;58:369-373. doi: 10.1016/j.gaitpost.2017.08.016. Epub 2017 Aug 31.

Abstract

This study examined whether epidural injection-induced anesthesia acutely and positively affected temporal spatial parameters of gait in patients with chronic low back pain (LBP) due to lumbar spinal stenosis. Twenty-five patients (61.7±13.6years) who were obtaining lumbar epidural injections for stenosis-related LBP participated. Oswestry Disability Index (ODI) scores, Medical Outcomes Short Form (SF-36) scores, 11-point Numerical pain rating (NRS) scores, and temporal spatial parameters of walking gait were obtained prior to, and 11-point Numerical pain rating (NRS) scores, and temporal spatial parameters of walking gait were obtained after the injection. Gait parameters were measured using an instrumented gait mat. Patients received transforaminal epidural injections in the L1-S1 vertebral range (1% lidocaine, corticosteroid) under fluoroscopic guidance. Patients with post-injection NRS ratings of "0" or values greater than "0" were stratified into two groups: 1) full pain relief, or 2) partial pain relief, respectively. Post-injection, 48% (N=12) of patients reported full pain relief. ODI scores were higher in patients with full pain relief (55.3±21.4 versus 33.7 12.8; p=0.008). Post-injection, stride length and step length variability were significantly improved in the patients with full pain relief compared to those with partial pain relief. Effect sizes between full and partial pain relief for walking velocity, step length, swing time, stride and step length variability were medium to large (Cohen's d>0.50). Patients with LBP can gain immediate gait improvements from complete pain relief from transforaminal epidural anesthetic injections for LBP, which could translate to better stability and lower fall risk.

摘要

本研究探讨了硬膜外注射诱导的麻醉是否会对因腰椎管狭窄导致慢性下腰痛(LBP)患者的步态时空参数产生急性且积极的影响。25名因狭窄相关LBP接受腰椎硬膜外注射的患者(61.7±13.6岁)参与了研究。在注射前获取Oswestry功能障碍指数(ODI)评分、医学结局简表(SF - 36)评分、11点数字疼痛评分(NRS)以及步行步态的时空参数,注射后获取11点数字疼痛评分(NRS)以及步行步态的时空参数。使用仪器化步态垫测量步态参数。患者在透视引导下于L1 - S1椎体范围接受经椎间孔硬膜外注射(1%利多卡因、皮质类固醇)。注射后NRS评分为“0”或大于“0”的患者被分为两组:1)完全疼痛缓解,或2)部分疼痛缓解。注射后,48%(N = 12)的患者报告完全疼痛缓解。完全疼痛缓解的患者ODI评分更高(55.3±21.4对33.7±12.8;p = 0.008)。注射后,与部分疼痛缓解的患者相比,完全疼痛缓解的患者步长和步长变异性显著改善。完全疼痛缓解与部分疼痛缓解之间在步行速度、步长、摆动时间、步幅和步长变异性方面的效应大小为中等至较大(科恩d>0.50)。LBP患者可通过经椎间孔硬膜外麻醉注射完全缓解疼痛而立即改善步态,这可能转化为更好的稳定性和更低的跌倒风险。

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