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葡萄牙南部地区自发性脑出血的发病率和病死率。

Incidence and case-fatality from spontaneous intracerebral hemorrhage in a southern region of Portugal.

机构信息

Department of Clinical Medicine, University of Bergen, Bergen, Norway; Department of Biomedical Sciences and Medicine, University of Algarve, Faro, Portugal.

Department of Biomedical Sciences and Medicine, University of Algarve, Faro, Portugal.

出版信息

J Neurol Sci. 2017 Sep 15;380:74-78. doi: 10.1016/j.jns.2017.07.006. Epub 2017 Jul 8.

Abstract

BACKGROUND

There is scarce information on incidence and case fatality of spontaneous intracerebral hemorrhage (SICH) in certain regions of the world, including in Europe. There is no community-based data on SICH in Southern Portugal.

AIM

To determine the incidence and early case-fatality from SICH in Algarve, the southernmost region of Portugal.

METHODS

The recommended criteria for stroke incidence studies was used to identify cases of incident first-ever SICH from January 1st to December 31st 2015 in a subregion with 280,081 inhabitants. Crude incidence rates per age group and gender; standardized rates to the European population; and age adjusted case fatality rates were calculated.

RESULTS

Eighty-two first-ever cases of SICH (64.6% men) occurred. The mean age was 72.3 years (SD±12.1); women were 3 years older than men on average and had more frequently lobar SICH. The crude annual incidence rate was 29.2/100,000 (95% CI 23.4- 38.6; p<0.001); higher in men (39.7/100,000) than women (19.8/100,000). The standardized to the European population incidence was 15.1/100,000 (95% CI 3.6-18.9; p<0.05); 26.9 and 10.9/100,000 for men and women respectively. The 30-day case-fatality was 40 % (95% CI 29-51) and increased steeply with age CONCLUSION: The incidence of SICH in Southern Portugal was high, but within the figures found in some parts of Europe. However, a marked predominance of males was found and the case-fatality rate was amongst the highest reported in western countries.

摘要

背景

世界上某些地区,包括欧洲,关于自发性脑出血(SICH)的发病率和病死率的信息很少。在葡萄牙南部,没有关于 SICH 的社区数据。

目的

确定葡萄牙南部阿尔加维地区 SICH 的发病率和早期病死率。

方法

采用推荐的卒中发病率研究标准,于 2015 年 1 月 1 日至 12 月 31 日,在一个拥有 280081 名居民的亚区域中,识别首次发生的 SICH 病例。计算各年龄组和性别的粗发病率;按欧洲人口标准化发病率;以及年龄调整病死率。

结果

共发生 82 例首次 SICH(64.6%为男性)。平均年龄为 72.3 岁(标准差±12.1);女性平均比男性年长 3 岁,且更常发生脑叶 SICH。粗年发病率为 29.2/100000(95%置信区间 23.4-38.6;p<0.001);男性(39.7/100000)高于女性(19.8/100000)。按欧洲人口标准化发病率为 15.1/100000(95%置信区间 3.6-18.9;p<0.05);男性为 26.9/100000,女性为 10.9/100000。30 天病死率为 40%(95%置信区间 29-51),且随年龄急剧增加。

结论

葡萄牙南部 SICH 的发病率较高,但在欧洲部分地区的发病率范围内。然而,发现男性发病率明显较高,病死率在西方国家中属于较高之列。

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