小鼠单侧肾切除术后肾脏中的代偿性细胞增殖。
Compensatory cell proliferation in the kidney after unilateral nephrectomy in mice.
作者信息
Skraastad O
出版信息
Virchows Arch B Cell Pathol Incl Mol Pathol. 1987;53(2):97-101. doi: 10.1007/BF02890230.
PMID:2887063
Abstract
The compensatory cell proliferation in kidney cortex after unilateral nephrectomy in hair-less mice was evaluated by registration of the mitotic rate, thymidine incorporation into DNA, and labelling indices (LI) over a period of 120 h after surgery. Maximal specific activity of DNA and LI were found at 30-36 h postoperatively and preceded the maximal mitotic rate by 6-12 h. The influence of age, sex and diurnal variations was examined.
摘要
通过记录无毛小鼠单侧肾切除术后120小时内的有丝分裂率、胸腺嘧啶核苷掺入DNA的情况以及标记指数（LI），评估肾皮质的代偿性细胞增殖。术后30 - 36小时发现DNA的最大比活性和标记指数，且比最大有丝分裂率早6 - 12小时出现。研究了年龄、性别和昼夜变化的影响。
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