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儿童意外摄入左甲状腺素的临床效应

Clinical effects of accidental levothyroxine ingestion in children.

作者信息

Golightly L K, Smolinske S C, Kulig K W, Wruk K M, Gelman C J, Rumack B H, Linden C H

出版信息

Am J Dis Child. 1987 Sep;141(9):1025-7. doi: 10.1001/archpedi.1987.04460090102039.

DOI:10.1001/archpedi.1987.04460090102039
PMID:2887106
Abstract

Forty-one children, aged 1 to 5 years, who accidentally ingested levothyroxine sodium were studied. Symptoms possibly associated with the ingestion occurred in 11 patients (27%). These symptoms (tachycardia, hyperactive behavior, fever, vomiting, diarrhea, diaphoresis, and flushing) were categorized as minor and all resolved without treatment. Because observed effects were generally mild and often unrelated to either estimated amounts of hormone consumed or serum thyroxine levels, a conservative approach to patient treatment is recommended in cases of levothyroxine ingestion in children.

摘要

对41名1至5岁意外摄入左甲状腺素钠的儿童进行了研究。11名患者(27%)出现了可能与摄入相关的症状。这些症状(心动过速、多动行为、发热、呕吐、腹泻、多汗和潮红)被归类为轻微症状,且未经治疗均已缓解。由于观察到的影响通常较轻,且往往与估计摄入的激素量或血清甲状腺素水平无关,因此对于儿童摄入左甲状腺素的情况,建议采取保守的患者治疗方法。

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Clinical effects of accidental levothyroxine ingestion in children.儿童意外摄入左甲状腺素的临床效应
Am J Dis Child. 1987 Sep;141(9):1025-7. doi: 10.1001/archpedi.1987.04460090102039.
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Levothyroxine ingestions in children: an analysis of 78 cases.儿童左甲状腺素摄入:78例病例分析。
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Benign course after massive levothyroxine ingestion.大量摄入左甲状腺素后病情呈良性发展。
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