Healing Response of a Structural Hamstring Injury: Perfusion Imaging 8-Week Follow-Up.

CONTEXT

Hamstring injuries are frequently observed in various sports disciplines both in elite and recreational sport.

OBJECTIVE

To quantify intramuscular tissue perfusion via contrast-enhanced ultrasound in the acute phase and during the healing of a structural muscle injury confirmed by high-resolution magnetic resonance imaging.

DESIGN

Case study.

SETTING

Laboratory environment.

PATIENT

A 32-year-old wakeboarder (height = 176 cm, body weight = 76 kg, and body mass index = 24.5 kg/m2) with an acute indirect muscle injury of the semimembranosus muscle.

MAIN OUTCOME MEASURES

Average values of quantifiable contrast-enhanced ultrasound, represented as peak enhancement and wash-in area under the curve, as well as conventional ultrasound, 1.5T magnetic resonance imaging were assessed at 48-hour, 3-week, and 8-week postinjury.

RESULTS

Average values of the quantitative perfusion analysis at 48-hour and 8-week postinjury revealed an approximate 5-fold increase in peak enhancement, and the wash-in area under the curve increased more than 3-fold in the center of the lesion. Magnetic resonance imaging, performed 48 hours after the injury to gather reference data as gold standard, revealed a grade III structural muscle tear.

CONCLUSIONS

The authors are able to demonstrate significant changes in intramuscular tissue perfusion in the center of the structural lesion as well as in the adjacent tissue. Quantifiable contrast-enhanced ultrasound seems to be able to gather relevant data for the assessment and monitoring of muscle injuries and could be established as a valuable tool for further studies focusing on healing processes or therapeutic interventions.