68Ga-DOTA-TATE PET/CT 用于转移性上皮样血管内皮细胞瘤中生长抑素受体表达的分子成像：与 18F-FDG 的比较。

68Ga-DOTA-TATE PET/CT for Molecular Imaging of Somatostatin Receptor Expression in Metastasizing Epithelioid Hemangioendothelioma: Comparison With 18F-FDG.

机构信息

From the Departments of *Nuclear Medicine, and †Diagnostic and Interventional Radiology, and ‡Institute of Pathology, Hannover Medical School, Hannover, Germany.

出版信息

Clin Nucl Med. 2017 Nov;42(11):e478-e479. doi: 10.1097/RLU.0000000000001814.

DOI:10.1097/RLU.0000000000001814

PMID:28872546

Abstract

Epithelioid hemangioendothelioma (EHE) is a rare tumor originating from vascular endothelial or pre-endothelial cells. It has the potential to metastasize. We present the case of a 51-year-old woman with metastasizing EHE who underwent both F-FDG and Ga-DOTA-TATE PET/CT for staging of disease and for evaluation of targeted radionuclide therapy potential. On Ga-DOTA-TATE PET scans, intense tracer accumulation was observed in metastases. Besides the increased glucose metabolism in EHE, this case highlights the potential of Ga-DOTA-TATE PET/CT for restaging of EHE and the option of targeted radionuclide therapy in this entity.

摘要

上皮样血管内皮细胞瘤（EHE）是一种罕见的起源于血管内皮或前内皮细胞的肿瘤。它具有转移的潜力。我们报告了一例 51 岁女性转移性 EHE 患者，她接受了 F-FDG 和 Ga-DOTA-TATE PET/CT 进行疾病分期和评估靶向放射性核素治疗的潜力。在 Ga-DOTA-TATE PET 扫描中，观察到转移灶有强烈的示踪剂积聚。除了 EHE 中葡萄糖代谢增加外，本病例还强调了 Ga-DOTA-TATE PET/CT 对 EHE 再分期的潜力以及该实体中靶向放射性核素治疗的选择。