酸中毒期间比目鱼和虹鳟鱼心脏组织中的电活动和机械活动。

Electrical and mechanical activity in heart tissue of flounder and rainbow trout during acidosis.

Höglund L, Gesser H

Comp Biochem Physiol A Comp Physiol. 1987;87(3):543-6. doi: 10.1016/0300-9629(87)90357-4.

Abstract

Twitch force and voltage across the sarcolemma were measured in heart tissue of flounder and rainbow trout. 2. For the trout heart, hypercapnia was followed by a loss of force and an action potential prolongation. 3. This was also observed for the flounder heart, but only initially. 4. About 5 min after the onset of hypercapnia, an increase in force and a shortening of the action potential occurred in the flounder heart. 5. After about 30 min of hypercapnia a decrease in force and a prolongation of the action potential slowly appeared. 6. These results can be interpreted in terms of a species-dependent effect of acidosis on the cellular Ca2+ handling and the influence of intracellular Ca2+ on the action potential.

摘要

在比目鱼和虹鳟鱼的心脏组织中测量了肌纤维抽搐力和肌膜上的电压。2. 对于鳟鱼心脏，高碳酸血症之后出现力量丧失和动作电位延长。3. 在比目鱼心脏中也观察到了这一现象，但仅在最初阶段。4. 高碳酸血症开始约5分钟后，比目鱼心脏出现力量增加和动作电位缩短。5. 高碳酸血症约30分钟后，力量逐渐下降，动作电位延长。6. 这些结果可以从酸中毒对细胞钙处理的物种依赖性效应以及细胞内钙对动作电位的影响方面来解释。