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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Comp Biochem Physiol A Comp Physiol. 1987;87(3):703-9. doi: 10.1016/0300-9629(87)90386-0.

The measurement of fluid volumes by the indicator dilution technique and compartmental analysis was re-evaluated in free-swimming, undisturbed rainbow trout. 2. Plasma (33.5 ml/kg body wt) and blood (41.3 ml/kg body wt) volumes estimated by compartmental analysis from blood samples taken early (less than 5 min) after dye injection were 40% lower than volumes calculated by sampling late (greater than or equal to 80 min). 3. The rate of exchange of dye between plasma and interstitial fluid was high (48%/hr) compared to mammals (5%/hr) which supports the hypothesis that teleost capillaries have high protein permeability. 4. Total extracellular volume estimated using a single pool model (210.5 ml/kg body wt) of inulin kinetics was 20% higher than that calculated by a three pool model (172.8 ml/kg body wt).

采用指示剂稀释技术和房室分析对自由游动、未受干扰的虹鳟鱼的液体体积测量进行了重新评估。2. 通过对染料注射后早期（少于5分钟）采集的血样进行房室分析估计的血浆（33.5毫升/千克体重）和血液（41.3毫升/千克体重）体积，比后期（大于或等于80分钟）采样计算出的体积低40%。3. 与哺乳动物（5%/小时）相比，血浆与组织间液之间染料的交换速率较高（48%/小时），这支持了硬骨鱼毛细血管具有高蛋白通透性的假说。4. 使用菊粉动力学单池模型（210.5毫升/千克体重）估计的总细胞外体积比三池模型（172.8毫升/千克体重）计算出的体积高20%。

Comp Biochem Physiol A Comp Physiol. 1987;87(3):703-9. doi: 10.1016/0300-9629(87)90386-0.

The measurement of fluid volumes by the indicator dilution technique and compartmental analysis was re-evaluated in free-swimming, undisturbed rainbow trout. 2. Plasma (33.5 ml/kg body wt) and blood (41.3 ml/kg body wt) volumes estimated by compartmental analysis from blood samples taken early (less than 5 min) after dye injection were 40% lower than volumes calculated by sampling late (greater than or equal to 80 min). 3. The rate of exchange of dye between plasma and interstitial fluid was high (48%/hr) compared to mammals (5%/hr) which supports the hypothesis that teleost capillaries have high protein permeability. 4. Total extracellular volume estimated using a single pool model (210.5 ml/kg body wt) of inulin kinetics was 20% higher than that calculated by a three pool model (172.8 ml/kg body wt).

采用指示剂稀释技术和房室分析对自由游动、未受干扰的虹鳟鱼的液体体积测量进行了重新评估。2. 通过对染料注射后早期（少于5分钟）采集的血样进行房室分析估计的血浆（33.5毫升/千克体重）和血液（41.3毫升/千克体重）体积，比后期（大于或等于80分钟）采样计算出的体积低40%。3. 与哺乳动物（5%/小时）相比，血浆与组织间液之间染料的交换速率较高（48%/小时），这支持了硬骨鱼毛细血管具有高蛋白通透性的假说。4. 使用菊粉动力学单池模型（210.5毫升/千克体重）估计的总细胞外体积比三池模型（172.8毫升/千克体重）计算出的体积高20%。