Martins Carla, Assunção Ricardo, Cunha Sara C, Fernandes José O, Jager Alessandra, Petta Tânia, Oliveira Carlos Augusto, Alvito Paula
Food and Nutrition Department, National Institute of Health Doutor Ricardo Jorge, Av. Padre Cruz, 1649-016 Lisboa, Portugal; National School of Public Health, NOVA University of Lisboa, Av. Padre Cruz, 1649-016 Lisboa, Portugal; CESAM, Centre for Environmental and Marine Studies, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal.
Food and Nutrition Department, National Institute of Health Doutor Ricardo Jorge, Av. Padre Cruz, 1649-016 Lisboa, Portugal; CESAM, Centre for Environmental and Marine Studies, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal; IIFA, Universidade de Évora, Palácio do Vimioso, Largo Marquês de Marialva, Apartado 94, 7002-554 Évora, Portugal.
Food Chem. 2018 Jan 15;239:132-140. doi: 10.1016/j.foodchem.2017.06.088. Epub 2017 Jun 17.
Mycotoxins are secondary metabolites of fungi that cause toxic and carcinogenic effects. Human exposure to multiple mycotoxins constitutes an increasing health concern due to potential mycotoxins combined effects. The presence of mycotoxins mixtures in foodstuffs as cereals has been reported over the last years, but few studies are available concerning its occurrence in cereals primarily marketed for children, a particular vulnerable population group. The present study aims to assess the co-occurrence of twenty-one mycotoxins and metabolites present in breakfast cereals primarily marketed for children in Portugal. Results showed that 96% of the analysed breakfast cereal samples were contaminated with several mycotoxins. Twenty-two combinations were identified including two to seven different mycotoxins. Conclusions pointed out an urgent need to review legislative limits in food matrices consumed by children and to perform a more accurate risk assessment of children's exposure to mycotoxins mixtures in food.
霉菌毒素是真菌的次生代谢产物，会产生毒性和致癌作用。由于潜在的霉菌毒素联合效应，人类接触多种霉菌毒素对健康构成了日益严重的威胁。过去几年已有报道称食品（如谷物）中存在霉菌毒素混合物，但针对主要面向儿童（一个特别脆弱的人群）销售的谷物中霉菌毒素混合物的存在情况，相关研究较少。本研究旨在评估葡萄牙主要面向儿童销售的早餐谷物中21种霉菌毒素及其代谢产物的共存情况。结果显示，96%的分析早餐谷物样本受到多种霉菌毒素污染。共鉴定出22种组合，包括2至7种不同的霉菌毒素。结论指出，迫切需要审查儿童食用的食品基质中的立法限量，并对儿童接触食品中霉菌毒素混合物进行更准确的风险评估。
