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肥大细胞与特发性男性不育症。

Mast cells and idiopathic male infertility.

作者信息

Agarwal S, Choudhury M, Banerjee A

出版信息

Int J Fertil. 1987 Jul-Aug;32(4):283-6.

PMID:2887525
Abstract

Eighty-three testicular biopsies, done for evaluation of oligozoospermia and azoospermia, were reviewed. Biopsies from eight healthy fertile males served as control. Johnsen's scoring was used for the staging of spermatogenesis. The number of mast cells was counted in a 1-mm2 area to study the relationship of spermatogenesis and mast cell proliferation. An impairment of spermatogenesis was noticed as the mast cell density increased. When the Johnsen score ranged between 1 and 4, mast cells were 24 to 112, with a mean of 57.7 cells/mm2. This value was highly significant when compared with control cases (P less than .001).

摘要

回顾了83例为评估少精子症和无精子症而进行的睾丸活检。来自8名健康有生育能力男性的活检组织作为对照。采用约翰森评分法对精子发生进行分期。在1平方毫米的区域内计数肥大细胞数量,以研究精子发生与肥大细胞增殖之间的关系。随着肥大细胞密度增加,观察到精子发生受损。当约翰森评分在1至4之间时,肥大细胞数量为24至112个,平均为57.7个/平方毫米。与对照病例相比,该值具有高度显著性(P小于0.001)。

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