Liu Jian-Xun, Ren Jian-Xun, Lin Cheng-Ren
Institute of Basic Medical Sciences of Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.
Zhongguo Zhong Yao Za Zhi. 2016 Mar;41(6):971-975. doi: 10.4268/cjcmm20160601.
The efficacy not only is summarized by clinical effect of Chinese herbal compound on theory of traditional Chinese medicine, but also is manifested to clinical effect by interaction of many intricate chemical substances. The efficacy of Chinese herbal compound is current research focus in field of traditional Chinese medicine. By currently knowing in different aspects which included the progression in efficacy of Chinese herbal compound, symptomatic efficacy of Chinese herbal compound, the relationship between the efficacy and pharmacologic effect of Chinese herbal compound, the efficacy related pharmacodynamic substance and the evaluation of efficacy, it had been summarized mainly problems and methods in research and development process of the efficacy of Chinese herbal compound in this paper. Paper also elucidated problems that need to pay attention in research of efficacy in order to provide references for clinical and experimental studies of efficacy in Chinese herbal compound, boost research and development level of new traditional Chinese drug and facilitate modernization of traditional Chinese medicines.
中药复方的功效不仅体现在基于中医理论的临床疗效总结上，还通过多种复杂化学物质的相互作用表现为临床效果。中药复方的功效是目前中医药领域的研究热点。通过目前从不同方面对中药复方功效的研究进展、症状疗效、功效与药理作用的关系、功效相关的药效物质以及功效评价等方面的了解，本文总结了中药复方功效研发过程中的主要问题及方法。本文还阐明了功效研究中需要注意的问题，为中药复方功效的临床及实验研究提供参考，提高中药新药的研发水平，促进中医药现代化。
