新发阴道毛滴虫感染与性伴关系并发率相关：一项纵向队列研究。
Incident Trichomonas vaginalis Is Associated With Partnership Concurrency: A Longitudinal Cohort Study.
作者信息
Kenyon Chris R, Buyze Jozefien, Klebanoff Mark, Brotman Rebecca M
机构信息
From the *HIV/STI Unit, Institute of Tropical Medicine, Antwerp, Belgium; †Department of Medicine, University of Cape Town, South Africa; ‡Clinical Trials Unit, Institute of Tropical Medicine, Antwerp, Belgium; §Department of Epidemiology, The Research Institute at Nationwide Children's Hospital, ∥Department of Pediatrics and Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, OH; and ¶Department of Epidemiology and Public Health, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD.
出版信息
Sex Transm Dis. 2017 Nov;44(11):695-699. doi: 10.1097/OLQ.0000000000000668.
BACKGROUND
Sexual partner concurrency (PC) has been shown to be a risk factor for a number of sexually transmitted infections but it is unknown if it is a risk factor for Trichomonas vaginalis (TV).
OBJECTIVE
We assess if there is an association between PC and incident TV infection.
STUDY DESIGN
We used mixed effects logistic regression to assess the association between PC and incident TV in the Longitudinal Study of Vaginal Flora, a cohort study of 3620 women followed quarterly for 5 visits.
RESULTS
Trichomonas vaginalis was more common in those reporting definite/possible/unknown PC (15.6%/15.0%/18.3%) than those reporting no PC (5.2%; P < 0.001 for all 3 comparisons). After controlling for a range of confounders, incident TV remained associated with reporting that one's partner definitely (adjusted odds ratio, 5.4; 95% confidence interval, 3.7-8.0) and possibly (adjusted odds ratio, 3.4; 95% confidence interval, 2.2-5.1) engaged in PC in the preceding period.
CONCLUSIONS
Partner concurrency was associated with incident TV infection.
背景
性伴侣同时存在多个性伴侣（性伴侣并发，PC）已被证明是多种性传播感染的危险因素，但尚不清楚它是否是阴道毛滴虫（TV）的危险因素。
目的
我们评估性伴侣并发与新发阴道毛滴虫感染之间是否存在关联。
研究设计
在阴道菌群纵向研究中，我们使用混合效应逻辑回归来评估性伴侣并发与新发阴道毛滴虫感染之间的关联。该队列研究对3620名女性进行了为期5次的季度随访。
结果
报告有明确/可能/未知性伴侣并发情况的女性中，阴道毛滴虫感染更为常见（分别为15.6%/15.0%/18.3%），高于报告无性伴侣并发情况的女性（5.2%；所有3组比较P均<0.001）。在控制一系列混杂因素后，新发阴道毛滴虫感染仍与报告在前一时期伴侣明确（调整优势比，5.4；95%置信区间，3.7 - 8.0）和可能（调整优势比，3.4；95%置信区间，2.2 - 5.1）存在性伴侣并发情况有关。
结论
性伴侣并发与新发阴道毛滴虫感染有关。
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