HIV/STI Reference Laboratory, Department of Microbiology, Institute of Tropical Medicine, Antwerp, Belgium.
Sex Transm Dis. 2010 Apr;37(4):223-7. doi: 10.1097/OLQ.0b013e3181c21f93.
The aim of the study was to assess the prevalence of Trichomonas sp. infection among adolescent girls, pregnant women, and commercial sex workers in Ndola, Zambia.
A cross-sectional study was conducted among 460 girls attending school, 307 pregnant women, and 197 commercial sex workers. Self-collected specimens from the vagina, rectum, and mouth were tested by polymerase chain amplification assays for the presence of Trichomonas vaginalis, Pentatrichomonas hominis, and Trichomonas tenax. Genotyping was performed on specimens that tested positive for T. vaginalis.
The prevalence of vaginal infection with T. vaginalis was 24.6% among the adolescents, 32.2% among the pregnant women, and 33.2% among the commercial sex workers. Trichomonads other than T. vaginalis were rarely found in the vagina, rectum, and mouth. The presence of T. vaginalis in the rectum was associated with T. vaginalis in the vagina. T. tenax was also detected in the vagina. A total of 9 actin genotypes of T. vaginalis were identified. The distribution of the actin genotypes of T. vaginalis was similar in the 3 study groups.
We detected high prevalence rates of trichomoniasis among women in Ndola, Zambia. Prevalence among adolescent girls was lower than among pregnant women and commercial sex workers but was still high. We were not able to detect differences in T. vaginalis actin genotypes among the 3 study groups.
本研究旨在评估赞比亚恩多拉市少女、孕妇和性工作者中阴道毛滴虫感染的流行情况。
对在校的 460 名少女、307 名孕妇和 197 名性工作者进行了横断面研究。采用聚合酶链扩增法检测阴道、直肠和口腔的自我采集标本中是否存在阴道毛滴虫、五毛滴虫和阴道内毛滴虫。对阴道毛滴虫检测阳性的标本进行基因分型。
青少年、孕妇和性工作者的阴道毛滴虫感染率分别为 24.6%、32.2%和 33.2%。阴道、直肠和口腔中很少发现其他毛滴虫。直肠内存在阴道毛滴虫与阴道内存在阴道毛滴虫有关。阴道内也检测到阴道内毛滴虫。共鉴定出 9 种阴道毛滴虫的肌动蛋白基因型。3 个研究组中阴道毛滴虫肌动蛋白基因型的分布相似。
我们在赞比亚恩多拉市的妇女中检测到了高患病率的滴虫病。少女中的患病率低于孕妇和性工作者，但仍很高。我们未能检测到 3 个研究组中阴道毛滴虫肌动蛋白基因型的差异。
