• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding.

作者信息

Dodd Garron T, Andrews Zane B, Simonds Stephanie E, Michael Natalie J, DeVeer Michael, Brüning Jens C, Spanswick David, Cowley Michael A, Tiganis Tony

出版信息

Cell Metab. 2017 Sep 5;26(3):577. doi: 10.1016/j.cmet.2017.08.001.

DOI:10.1016/j.cmet.2017.08.001
PMID:28877462
Abstract
摘要

相似文献

1
A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding.一种下丘脑磷酸酶开关协调能量消耗与进食。
Cell Metab. 2017 Sep 5;26(3):577. doi: 10.1016/j.cmet.2017.08.001.
2
Gonadotropin-inhibitory hormone is a hypothalamic peptide that provides a molecular switch between reproduction and feeding.促性腺激素抑制激素是一种下丘脑肽,为生殖和摄食之间提供了分子开关。
Neuroendocrinology. 2012;95(4):305-16. doi: 10.1159/000332822. Epub 2012 Jan 25.
3
Role of malonyl-CoA in the hypothalamic control of food intake and energy expenditure.丙二酰辅酶A在下丘脑对食物摄入和能量消耗的控制中的作用。
Biochem Soc Trans. 2005 Nov;33(Pt 5):1063-7. doi: 10.1042/BST20051063.
4
Reduced energy expenditure and impaired feeding-related signals but not high energy intake reinforces hypothalamic obesity in adults with childhood onset craniopharyngioma.能量消耗减少和摄食相关信号受损,但能量摄入不高,这加剧了儿童期发病的颅咽管瘤患者的下丘脑性肥胖。
J Clin Endocrinol Metab. 2010 Dec;95(12):5395-402. doi: 10.1210/jc.2010-0993. Epub 2010 Sep 8.
5
Triiodothyronine stimulates food intake via the hypothalamic ventromedial nucleus independent of changes in energy expenditure.三碘甲状腺原氨酸通过下丘脑腹内侧核刺激食物摄入,而与能量消耗的变化无关。
Endocrinology. 2004 Nov;145(11):5252-8. doi: 10.1210/en.2004-0545. Epub 2004 Aug 5.
6
Tail suspension increases energy expenditure independently of the melanocortin system in mice.尾部悬吊增加了能量消耗,而与小鼠的黑皮质素系统无关。
Can J Physiol Pharmacol. 2009 Oct;87(10):839-49. doi: 10.1139/Y09-074.
7
Melanocortinergic activation by melanotan II inhibits feeding and increases uncoupling protein 1 messenger ribonucleic acid in the developing rat.黑素皮质素受体激动剂二型黑素细胞刺激素对发育中的大鼠的作用是抑制进食并增加解偶联蛋白1信使核糖核酸。
Endocrinology. 2007 Jul;148(7):3279-87. doi: 10.1210/en.2007-0184. Epub 2007 Apr 5.
8
Evidence for the existence of distinct central appetite, energy expenditure, and ghrelin stimulation pathways as revealed by hypothalamic site-specific leptin gene therapy.下丘脑位点特异性瘦素基因治疗揭示的不同中枢食欲、能量消耗和胃饥饿素刺激途径存在的证据。
Endocrinology. 2002 Nov;143(11):4409-21. doi: 10.1210/en.2002-220505.
9
Regulation of food intake and energy expenditure by hypothalamic malonyl-CoA.下丘脑丙二酰辅酶A对食物摄入和能量消耗的调节
Int J Obes (Lond). 2008 Sep;32 Suppl 4:S49-54. doi: 10.1038/ijo.2008.123.
10
Targeting intermediary metabolism in the hypothalamus as a mechanism to regulate appetite.以下丘脑中间代谢为靶点调节食欲的机制。
Pharmacol Rev. 2010 Jun;62(2):237-64. doi: 10.1124/pr.109.002428. Epub 2010 Apr 14.

引用本文的文献

1
Neuronal Regulation of Feeding and Energy Metabolism: A Focus on the Hypothalamus and Brainstem.摄食与能量代谢的神经元调节:聚焦于下丘脑和脑干
Neurosci Bull. 2025 Apr;41(4):665-675. doi: 10.1007/s12264-024-01335-7. Epub 2024 Dec 20.
2
Site-Specifically Modified Peptide Inhibitors of Protein Tyrosine Phosphatase 1B and T-Cell Protein Tyrosine Phosphatase with Enhanced Stability and Improved In Vivo Long-Acting Activity.具有增强稳定性和改善体内长效活性的蛋白酪氨酸磷酸酶1B和T细胞蛋白酪氨酸磷酸酶的位点特异性修饰肽抑制剂。
ACS Pharmacol Transl Sci. 2024 Apr 24;7(5):1426-1437. doi: 10.1021/acsptsci.4c00054. eCollection 2024 May 10.
3
The sympathetic nervous system in the 21st century: Neuroimmune interactions in metabolic homeostasis and obesity.
21 世纪的交感神经系统:代谢稳态和肥胖中的神经免疫相互作用。
Neuron. 2022 Nov 2;110(21):3597-3626. doi: 10.1016/j.neuron.2022.10.017.
4
Brown Adipose Tissue-A Translational Perspective.棕色脂肪组织——转化视角。
Endocr Rev. 2023 Mar 4;44(2):143-192. doi: 10.1210/endrev/bnac015.
5
Multiple Leptin Signalling Pathways in the Control of Metabolism and Fertility: A Means to Different Ends?多种瘦素信号通路在代谢和生殖调控中的作用:殊途同归?
Int J Mol Sci. 2021 Aug 26;22(17):9210. doi: 10.3390/ijms22179210.
6
Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding.解析 AgRP-血清素能神经回路在能量代谢和摄食方面的不同控制作用。
Nat Commun. 2021 Jun 10;12(1):3525. doi: 10.1038/s41467-021-23846-x.
7
Brain insulin signalling in metabolic homeostasis and disease.脑胰岛素信号在代谢稳态和疾病中的作用。
Nat Rev Endocrinol. 2021 Aug;17(8):468-483. doi: 10.1038/s41574-021-00498-x. Epub 2021 Jun 9.
8
The brain as an insulin-sensitive metabolic organ.大脑作为一个对胰岛素敏感的代谢器官。
Mol Metab. 2021 Oct;52:101234. doi: 10.1016/j.molmet.2021.101234. Epub 2021 Apr 15.
9
Incendiary Leptin.致炎瘦素。
Nutrients. 2020 Feb 13;12(2):472. doi: 10.3390/nu12020472.
10
Estradiol Protects Neuropeptide Y/Agouti-Related Peptide Neurons against Insulin Resistance in Females.雌二醇可保护女性神经肽 Y/肥胖相关肽神经元免受胰岛素抵抗的影响。
Neuroendocrinology. 2020;110(1-2):105-118. doi: 10.1159/000501560. Epub 2019 Jun 19.