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A research agenda for curing chronic hepatitis B virus infection.

作者信息

Alter Harvey, Block Timothy, Brown Nathaniel, Brownstein Alan, Brosgart Carol, Chang Kyong-Mi, Chen Pei-Jer, Chisari Francis V, Cohen Chari, El-Serag Hashem, Feld Jordan, Gish Robert, Glenn Jeffrey, Greten Tim, Guo Haitao, Guo Ju-Tao, Hoshida Yujin, Hu Jianming, Kowdley Kris V, Li Wenhui, Liang Jake, Locarnini Stephan, Lok Anna S, Mason William, McMahon Brian, Mehta Anand, Perrillo Robert, Revill Peter, Rice Charles M, Rinaudo JoAnn, Schinazi Raymond, Seeger Christoph, Shetty Kirty, Tavis John, Zoulim Fabien

机构信息

Clinical Center, National Institutes of Health, Bethesda, MD.

Hepatitis B Foundation and Baruch S. Blumberg Institute, Doylestown, PA.

出版信息

Hepatology. 2018 Mar;67(3):1127-1131. doi: 10.1002/hep.29509. Epub 2018 Jan 24.

DOI:10.1002/hep.29509
PMID:28877549
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5873273/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f0e/5873273/22ebee62960f/HEP-67-1127-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f0e/5873273/22ebee62960f/HEP-67-1127-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f0e/5873273/22ebee62960f/HEP-67-1127-g001.jpg

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Annual Report to the Nation on the Status of Cancer, 1975-2012, featuring the increasing incidence of liver cancer.《1975 - 2012年美国癌症现状年度报告》,重点关注肝癌发病率上升情况
Cancer. 2016 May 1;122(9):1312-37. doi: 10.1002/cncr.29936. Epub 2016 Mar 9.
3
Global strategies are required to cure and eliminate HBV infection.
宿主3' 瓣状核酸内切酶Mus81在共价闭合环状DNA形成过程中修剪乙型肝炎病毒松弛环状DNA的末端冗余方面发挥着关键作用。
PLoS Pathog. 2025 Feb 6;21(2):e1012918. doi: 10.1371/journal.ppat.1012918. eCollection 2025 Feb.
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The loss of hepatitis B virus receptor NTCP/SLC10A1 in human liver cancer cells is due to epigenetic silencing.乙型肝炎病毒受体 NTCP/SLC10A1 在人肝癌细胞中的丢失是由于表观遗传沉默所致。
J Virol. 2024 Oct 22;98(10):e0118724. doi: 10.1128/jvi.01187-24. Epub 2024 Sep 19.
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A Particle Gel Assay for Detection of Intracellular Hepatitis B Virus Subviral Particles in Cultured Cells.一种用于检测细胞内乙型肝炎病毒亚病毒颗粒的粒子凝胶检测法。
Methods Mol Biol. 2024;2837:89-97. doi: 10.1007/978-1-0716-4027-2_8.
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