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韩国江原道铁原郡非军事区附近居民中通过快速诊断试验检测到的弓形虫病血清流行率

Seroprevalence of Toxoplasmosis Detected by RDT in Residents near the DMZ (demilitarized zone) of Cheorwon-gun, Gangwon-do, Korea.

作者信息

Kim Yeong Hoon, Lee Jihoo, Kim Young-Eun, Ahn Seongkyu, Kim Tong-Soo, Hong Sung-Jong, Chong Chom-Kyu, Ahn Hye-Jin, Nam Ho-Woo

机构信息

Department of Ophthalmology, College of Medicine, Catholic University of Korea, Seoul 06591, Korea.

Genbody Inc., Cheonan 31116, Korea.

出版信息

Korean J Parasitol. 2017 Aug;55(4):385-389. doi: 10.3347/kjp.2017.55.4.385. Epub 2017 Aug 31.

Abstract

Seroprevalence of Toxoplasma gondii infection among the residents of Cheorwon-gun, Gangwon-do, Korea, which partly includes the demilitarized zone (DMZ), were surveyed for 4 years and evaluated by RDT using recombinant fragment of major surface antigen (SAG1A). Sera from 1336, 583, 526, and 583 adult residents were collected on a yearly basis from 2010 to 2013, respectively. The total positive seroprevalence was 19.3, 21.9, 23.4, and 26.8% from 2010 to 2013, respectively. The positive seroprevalence in men (23.6, 27.5, 29.5, 34.6%) was far higher than women (14.1, 18.3, 19.4, 21.4%), from 2010 to 2013, respectively. This high seroprevalence of toxoplasmosis in Cheorwon-gun may have been influenced in part by its geographical locality of the area as it includes the DMZ, where civilian access is strictly limited, thus creating a relatively isolated area that is a well-preserved habitat. Further research is necessary to study the epidemiology of toxoplasmosis in this area.

摘要

对韩国江原道铁原郡(该地区部分包括非军事区)居民的弓形虫感染血清流行率进行了为期4年的调查,并使用主要表面抗原(SAG1A)重组片段通过快速诊断试验(RDT)进行评估。分别于2010年至2013年每年收集1336名、583名、526名和583名成年居民的血清。2010年至2013年的总血清阳性率分别为19.3%、21.9%、23.4%和26.8%。2010年至2013年,男性的血清阳性率(分别为23.6%、27.5%、29.5%、34.6%)远高于女性(分别为14.1%、18.3%、19.4%、21.4%)。铁原郡弓形虫病的高血清流行率可能部分受到该地区地理位置的影响,因为它包括非军事区,平民进入受到严格限制,从而形成了一个相对孤立且保存完好的栖息地。有必要进一步研究该地区弓形虫病的流行病学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/638b/5594721/71145afe9573/kjp-55-4-385f1.jpg

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