Sugita Hideki, Shinohara Ryoji, Yokomichi Hiroshi, Suzuki Kohta, Yamagata Zentaro
Department of Hospital Pharmaceutics, School of Pharmacy, Showa University, Tokyo, Japan.
Faculty of Health Science, Health Science University, Tsuru, Japan.
Nagoya J Med Sci. 2017 Aug;79(3):313-321. doi: 10.18999/nagjms.79.3.313.
It has been suggested that low health literacy (HL) is associated with poor medication adherence. This study aimed to examine the effect of a text message-based HL intervention to promote medication adherence, compared with text messages that only sent medication reminders, in patients with type 2 diabetes. This was a single-center, open-label, randomized (1:1) controlled pilot study. The study period was 6 months. Intervention group was sent HL related text messages, compared to the reminder messages that were sent to the control group. The primary outcome was the difference in the change rate of scores on the Morisky Eight-Item Medication Adherence Scale (MMAS-8). Forty-one participants were randomized into the intervention (n = 21) and control (n = 20) groups and completed the 6-month follow-up. Although almost participants read and understood the information provided in the messages, no significant difference was observed between groups for the primary outcome ( = 0.78). Our results suggested that medication adherence at 6 months after discharge in patients with type 2 diabetes did not significantly change by text messages, which aimed to improve their HL levels.
有人认为，健康素养低与用药依从性差有关。本研究旨在比较基于短信的健康素养干预与仅发送用药提醒的短信对2型糖尿病患者用药依从性的影响。这是一项单中心、开放标签、随机（1:1）对照的试点研究。研究期为6个月。干预组收到与健康素养相关的短信，而对照组收到提醒短信。主要结局是Morisky八项用药依从性量表（MMAS-8）得分变化率的差异。41名参与者被随机分为干预组（n = 21）和对照组（n = 20），并完成了6个月的随访。尽管几乎所有参与者都阅读并理解了短信中提供的信息，但两组在主要结局方面未观察到显著差异（ = 0.78）。我们的结果表明，旨在提高2型糖尿病患者健康素养水平的短信并未显著改变患者出院6个月后的用药依从性。
