Gao Siheng, Li Lijie, Vohra Ismail, Zha Daijun, You Lei
State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, People's Republic of China.
University of Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
R Soc Open Sci. 2017 Aug 30;4(8):170466. doi: 10.1098/rsos.170466. eCollection 2017 Aug.
As one of common dynamic covalent bonds, acylhydrazone bond plays an important role in developing intelligent responsive materials. In this report, we present acylhydrazone-based dynamic polymers with multi-stimuli responsiveness, particularly metal recognition behaviours and their modulation. A series of polyacylhydrazones with different metal-binding sites were designed and prepared in a modular fashion. Titration of these receptors with a diverse set of metal ions, including Cu, Zn and La, resulted in unique optical changes, and both the sensitivity and selectivity profiles can be regulated. Moreover, the metal-binding feature was facilely modulated by changing the solvent. The addition of weakly basic anions was employed to further fine-tune the responsiveness of the polymers by taking advantage of the cooperative effect with metal coordination. Finally, the sensitive detection of 6-mercaptopurine and pyrophosphate was achieved to demonstrate the application potential of these systems.
作为常见的动态共价键之一，酰腙键在开发智能响应材料中起着重要作用。在本报告中，我们展示了具有多刺激响应性，特别是金属识别行为及其调控的基于酰腙的动态聚合物。以模块化方式设计并制备了一系列具有不同金属结合位点的聚酰腙。用包括铜、锌和镧在内的多种金属离子滴定这些受体，导致独特的光学变化，并且灵敏度和选择性概况均可调节。此外，通过改变溶剂可轻松调节金属结合特性。利用与金属配位的协同效应，加入弱碱性阴离子以进一步微调聚合物的响应性。最后，实现了对6-巯基嘌呤和焦磷酸的灵敏检测，以证明这些体系的应用潜力。
