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一项关于在接受正中多生牙手术切除的儿童中联合使用镇静剂进行深度镇静的回顾性研究。

A retrospective study of deep sedation with concomitant administration of sedative agents in children undergoing surgical removal of a mesiodens.

作者信息

Lee Soo Jeong, Baek Kwangwoo

机构信息

Division of Pediatric Dentistry, Department of Dentistry, Ajou University School of Medicine, Suwon, Korea.

出版信息

J Dent Anesth Pain Med. 2015 Dec;15(4):213-220. doi: 10.17245/jdapm.2015.15.4.213. Epub 2015 Dec 31.

DOI:10.17245/jdapm.2015.15.4.213
PMID:28879282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5564157/
Abstract

BACKGROUND

Pediatric dentists face challenges when young patients require a mesiodens extraction. General anesthesia may be a burden to the child as well as the parent due to dental fears and costs. The aim of this study was to evaluate oral and intravenous sedation in the outpatient setting as a safe and effective means of managing patients who require a mesiodens extraction.

METHODS

Records were reviewed retrospectively to find patients who underwent a mesiodens removal procedure from January 2013 to September 2014 in the Department of Pediatric Dentistry at Ajou University Hospital (Suwon, Gyeonggi-do, Republic of Korea). A total of 81 patients (62 male and 19 female) between 4 and 11 years of age (mean [± SD] 81.6 ± 14.1 months) were studied, with a mean weight of 22.9 ± 3.3 kg (16 kg to 30 kg). Vital signs, sedation drug dosage, and sedation time were studied.

RESULTS

Mean doses of 63.7 ± 2.5 mg/kg chloral hydrate and 1.36 ± 0.22 mg/kg hydroxyzine were used for oral sedation. Nitrous oxide/oxygen was administrated for 40.0 ± 2.1 min. The mean dose of midazolam administered intravenously was 0.14 ± 0.06 mg/kg (2.38 ± 0.97 times). In all cases, the mesiodens was removed successfully.

CONCLUSIONS

Intravenous sedation combined with oral sedation and nitrous oxide/oxygen inhalation can be an alternative to general anesthesia when administrated and monitored properly.

摘要

背景

当年轻患者需要拔除多生牙时,儿童牙医面临挑战。由于牙科恐惧和费用问题,全身麻醉可能对儿童及其家长都是一种负担。本研究的目的是评估门诊环境下的口服和静脉镇静作为管理需要拔除多生牙患者的一种安全有效的方法。

方法

回顾性查阅记录,以找出2013年1月至2014年9月在韩国京畿道水原市阿朱大学医院儿科牙科接受多生牙拔除手术的患者。共研究了81例年龄在4至11岁(平均[±标准差]81.6±14.1个月)的患者,平均体重为22.9±3.3千克(16千克至30千克)。研究了生命体征、镇静药物剂量和镇静时间。

结果

口服镇静使用的水合氯醛平均剂量为63.7±2.5毫克/千克,羟嗪平均剂量为1.36±0.22毫克/千克。一氧化二氮/氧气给药40.0±2.1分钟。静脉注射咪达唑仑的平均剂量为0.14±0.06毫克/千克(2.38±0.97倍)。在所有病例中,多生牙均成功拔除。

结论

当正确给药和监测时,静脉镇静联合口服镇静和一氧化二氮/氧气吸入可作为全身麻醉的替代方法。

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本文引用的文献

1
Sedative Effect of Oral Midazolam/Hydroxyzine versus Chloral Hydrate/Hydroxyzine on 2-6 Year-Old Uncooperative Dental Patients: A Randomized Clinical Trial.口服咪达唑仑/羟嗪与水合氯醛/羟嗪对2至6岁不合作牙科患者的镇静效果:一项随机临床试验。
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Molecular genetics of supernumerary tooth formation.额外牙形成的分子遗传学
Genesis. 2011 Apr;49(4):261-77. doi: 10.1002/dvg.20715. Epub 2011 Apr 1.
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An observational study of the frequency of supernumerary teeth in a population of 2000 patients.一项针对2000名患者群体中多生牙发生率的观察性研究。
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Location, complications and treatment of mesiodentes--a retrospective study in children.正中多生牙的位置、并发症及治疗——一项儿童回顾性研究
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Mesiodens--diagnosis and management of a common supernumerary tooth.正中多生牙——一种常见多生牙的诊断与处理
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Mesiodens: a clinical and radiographic study.正中多生牙:一项临床与影像学研究。
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Project USAP 2000--use of sedative agents by pediatric dentists: a 15-year follow-up survey.美国儿牙医师协会2000项目——儿科牙医使用镇静剂情况:一项为期15年的随访调查
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Behavioral management strategies for young pediatric dental patients with disabilities.针对残疾小儿牙科患者的行为管理策略。
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Dental treatment for people with challenging behaviour: general anaesthesia or sedation?对行为具有挑战性的人群进行牙科治疗:全身麻醉还是镇静?
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Br Dent J. 2000 Jan 22;188(2):63-4. doi: 10.1038/sj.bdj.4800390.