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感染与肾脏:热带地区的故事。

Infections and the kidney: a tale from the tropics.

机构信息

Department of Pediatric Nephrology, St John's National Academy of Health Sciences, Bangalore, India.

出版信息

Pediatr Nephrol. 2018 Aug;33(8):1317-1326. doi: 10.1007/s00467-017-3785-2. Epub 2017 Sep 6.

Abstract

Tropical infections are caused by a variety of bacteria, viruses and parasitic organisms across varying geographical regions and are more often reported in adults than in children. Most of the infections are acute, presenting as a febrile illness with involvement of multiple organ systems, including the kidney. The gamut of renal manifestations extends from asymptomatic urinary abnormalities to acute kidney injury and-albeit rarely-chronic kidney disease. Tropical infections can involve the glomerular, tubulointerstitial and vascular compartments of the kidney. Leptospirosis, malaria, dengue, rickettsial fever and schistosomiasis are the most prevalent tropical infections which affect the kidneys of children living in the tropics. In this review we discuss renal involvement in these most prevalent tropical infections.

摘要

热带传染病由各种细菌、病毒和寄生虫引起,分布于不同的地理区域,在成年人中的报告比在儿童中更为常见。大多数感染是急性的,表现为发热伴有多个器官系统受累,包括肾脏。肾脏表现的范围从无症状性尿液异常到急性肾损伤,尽管罕见,但也包括慢性肾脏病。热带传染病可累及肾脏的肾小球、肾小管间质和血管部分。钩端螺旋体病、疟疾、登革热、斑疹伤寒和血吸虫病是最常见的热带传染病,影响热带地区儿童的肾脏。在这篇综述中,我们讨论了这些最常见的热带传染病对肾脏的影响。

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