Laux G, König W
Acta Psychiatr Scand. 1987 Jul;76(1):64-70. doi: 10.1111/j.1600-0447.1987.tb02863.x.
During the past few years the problem of over-prescribing benzodiazepines has been increasingly discussed. However, up to now exact data on the extent of an abuse of these substances are relatively scarce and controversial. An analysis done at the Psychiatric State Hospital Weinsburg from 1974 to 1983 regarding the frequency of the diagnosis "Benzodiazepine-dependence" showed that in only 150 cases (0.5%) out of almost 33,000 admitted patients was the diagnosis benzodiazepine-abuse justified, with an increase since the year 1980. During a prospective study of the quarterly incidence in 1984, 18.5% of the patients admitted met the criterion of long-term use of benzodiazepines (continuous use for more than 3 months). Sociodemographic and clinical data are presented and an index of abuse/dependence is proposed.
在过去几年里,苯二氮䓬类药物过度处方的问题受到了越来越多的讨论。然而,到目前为止,关于这些物质滥用程度的确切数据相对较少且存在争议。1974年至1983年在魏恩斯堡精神病医院进行的一项关于“苯二氮䓬类药物依赖”诊断频率的分析表明,在近33000名入院患者中,只有150例(0.5%)被诊断为苯二氮䓬类药物滥用合理,且自1980年以来呈上升趋势。在1984年对季度发病率的前瞻性研究中,18.5%的入院患者符合长期使用苯二氮䓬类药物的标准(连续使用超过3个月)。文中呈现了社会人口统计学和临床数据,并提出了一个滥用/依赖指数。