Tahar Kais, Xu Jie, Herre Heinrich
Institute of Medical Informatics, Statistics and Epidemiology, Medical Faculty, Leipzig University.
Stud Health Technol Inform. 2017;243:165-169.
The formalization of expert knowledge enables a broad spectrum of applications employing ontologies as underlying technology. These include eLearning, Semantic Web and expert systems. However, the manual construction of such ontologies is time-consuming and thus expensive. Moreover, experts are often unfamiliar with the syntax and semantics of formal ontology languages such as OWL and usually have no experience in developing formal ontologies. To overcome these barriers, we developed a new method and tool, called Expert2OWL that provides efficient features to support the construction of OWL ontologies using GFO (General Formal Ontology) as a top-level ontology. This method allows a close and effective collaboration between ontologists and domain experts. Essentially, this tool integrates Excel spreadsheets as part of a pattern-based ontology development and refinement process. Expert2OWL enables us to expedite the development process and modularize the resulting ontologies. We applied this method in the field of Chinese Herbal Medicine (CHM) and used Expert2OWL to automatically generate an accurate Chinese Herbology ontology (CHO). The expressivity of CHO was tested and evaluated using ontology query languages SPARQL and DL. CHO shows promising results and can generate answers to important scientific questions such as which Chinese herbal formulas contain which substances, which substances treat which diseases, and which ones are the most frequently used in CHM.
专家知识的形式化使得一系列以本体作为基础技术的应用成为可能。这些应用包括电子学习、语义网和专家系统。然而,手动构建此类本体既耗时又昂贵。此外,专家通常不熟悉诸如OWL等形式本体语言的语法和语义,并且通常没有开发形式本体的经验。为了克服这些障碍,我们开发了一种新的方法和工具,称为Expert2OWL,它提供了高效的功能,以支持使用通用形式本体(GFO)作为顶层本体来构建OWL本体。这种方法允许本体论者和领域专家之间进行密切而有效的协作。从本质上讲,该工具将Excel电子表格集成到基于模式的本体开发和完善过程中。Expert2OWL使我们能够加快开发过程并将生成的本体模块化。我们将此方法应用于中草药(CHM)领域,并使用Expert2OWL自动生成了一个准确的本草学本体(CHO)。使用本体查询语言SPARQL和DL对CHO的表达能力进行了测试和评估。CHO显示出了有前景的结果,并且可以回答重要的科学问题,例如哪些中药方剂包含哪些物质、哪些物质治疗哪些疾病以及哪些是CHM中最常用的物质。