你是否为旅行做好了暴露后预防（PEP）和暴露前预防（PrEP）的准备？旅行者HIV感染的风险缓解措施。
Are you PEPped and PrEPped for travel? Risk mitigation of HIV infection for travelers.
作者信息
Brett-Major D M, Scott P T, Crowell T A, Polyak C S, Modjarrad K, Robb M L, Blazes D L
机构信息
Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD USA.
Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD USA.
出版信息
Trop Dis Travel Med Vaccines. 2016 Nov 28;2:25. doi: 10.1186/s40794-016-0042-9. eCollection 2016.
The HIV pandemic persists globally and travelers are at risk for infection by the Human Immunodeficiency Virus (HIV). While HIV-focused guidelines delineate risk stratification and mitigation strategies for people in their home communities, travel issues are not addressed. In this review, direct and indirect evidence on HIV risk among travelers is explored. The burgeoning practice of employing pre-exposure prophylaxis (PrEP) with anti-retroviral therapy in the non-travel setting is introduced, as well as the more established use of post-exposure prophylaxis (PEP). Challenges in applying these lessons to travelers are discussed, and a new guidelines process is scoped and recommended.
全球范围内，艾滋病疫情持续存在，旅行者面临感染人类免疫缺陷病毒（HIV）的风险。虽然针对HIV的指南明确了本国社区人群的风险分层和缓解策略，但未涉及旅行相关问题。在本综述中，我们探讨了旅行者中HIV风险的直接和间接证据。介绍了在非旅行环境中使用抗逆转录病毒疗法进行暴露前预防（PrEP）这一新兴做法，以及更成熟的暴露后预防（PEP）的使用情况。讨论了将这些经验应用于旅行者时面临的挑战，并规划并推荐了一个新的指南制定流程。
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