• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Inflammatory illness: Why the next wave of antidepressants may target the immune system.

作者信息

Wetsman Nicole

出版信息

Nat Med. 2017 Sep 8;23(9):1009-1011. doi: 10.1038/nm0917-1009.

DOI:10.1038/nm0917-1009
PMID:28886000
Abstract
摘要

相似文献

1
Inflammatory illness: Why the next wave of antidepressants may target the immune system.炎症性疾病：为何下一代抗抑郁药可能靶向免疫系统。
Nat Med. 2017 Sep 8;23(9):1009-1011. doi: 10.1038/nm0917-1009.
2
Depression is an inflammatory disease, but cell-mediated immune activation is the key component of depression.抑郁症是一种炎症性疾病，但细胞介导的免疫激活是抑郁症的关键组成部分。
Prog Neuropsychopharmacol Biol Psychiatry. 2011 Apr 29;35(3):664-75. doi: 10.1016/j.pnpbp.2010.06.014. Epub 2010 Jun 20.
3
On redefining the role of the immune system in psychiatric disease.重新定义免疫系统在精神疾病中的作用
Biol Psychiatry. 2006 Oct 15;60(8):796-8. doi: 10.1016/j.biopsych.2006.09.013.
4
The hygiene hypothesis and psychiatric disorders.卫生假说与精神疾病。
Trends Immunol. 2008 Apr;29(4):150-8. doi: 10.1016/j.it.2008.01.002. Epub 2008 Mar 6.
5
Bacterial mucosa cross-talk and pathophysiology of inflammation.细菌与黏膜的相互作用及炎症的病理生理学
J Pediatr Gastroenterol Nutr. 2009 Apr;48 Suppl 2:S49-51. doi: 10.1097/MPG.0b013e3181a11773.
6
Infection, inflammation, and mental illness. The body's immune response to infectious agents may imperil the brain.感染、炎症与精神疾病。人体对传染原的免疫反应可能危及大脑。
Harv Ment Health Lett. 2009 Oct;26(4):1-3.
7
[Pain and the immune system. Physiopathologic and clinical correlations].[疼痛与免疫系统。生理病理与临床关联]
Minerva Anestesiol. 1992 Oct;58(10):1131-41.
8
Immuno-neuroendocrino-neurochemical interaction in psychiatric disorders.
Prog Neuropsychopharmacol Biol Psychiatry. 2014 Jan 3;48:259-60. doi: 10.1016/j.pnpbp.2013.08.002. Epub 2013 Aug 26.
9
Oxidative stress: a potential link between emotional wellbeing and immune response.氧化应激：情绪健康与免疫反应之间的潜在联系。
Curr Opin Pharmacol. 2016 Aug;29:70-6. doi: 10.1016/j.coph.2016.06.006. Epub 2016 Jul 9.
10
Prescription drugs: uses and effects. Antidepressants: mental illness.处方药：用途与效果。抗抑郁药：精神疾病。
Nurs Stand. 2005;19(40):2 p following 72.

引用本文的文献

1
Beyond the Surface: Tracing the Evolution of Inflammatory Mechanism in Depression through Bibliometric Analysis.透过表面现象：通过文献计量分析追踪抑郁症炎症机制的演变
Endocr Metab Immune Disord Drug Targets. 2025 Jan 8. doi: 10.2174/0118715303325541241024060229.
2
Cool the Inflamed Brain: A Novel Anti-inflammatory Strategy for the Treatment of Major Depressive Disorder.冷却发炎的大脑：治疗重度抑郁症的一种新的抗炎策略。
Curr Neuropharmacol. 2024;22(5):810-842. doi: 10.2174/1570159X21666230809112028.
3
The Two-Faced Cytokine IL-6 in Host Defense and Diseases.

本文引用的文献

1
Replicable and Coupled Changes in Innate and Adaptive Immune Gene Expression in Two Case-Control Studies of Blood Microarrays in Major Depressive Disorder.在两项重大抑郁症病例对照血液微阵列研究中，先天和适应性免疫基因表达可重复和耦合的变化。
Biol Psychiatry. 2018 Jan 1;83(1):70-80. doi: 10.1016/j.biopsych.2017.01.021. Epub 2017 Jul 6.
2
Absolute Measurements of Macrophage Migration Inhibitory Factor and Interleukin-1-β mRNA Levels Accurately Predict Treatment Response in Depressed Patients.巨噬细胞迁移抑制因子和白细胞介素-1-β mRNA水平的绝对测量可准确预测抑郁症患者的治疗反应。
Int J Neuropsychopharmacol. 2016 Sep 30;19(10). doi: 10.1093/ijnp/pyw045. Print 2016 Oct.
3
两面性细胞因子白细胞介素 6 在宿主防御和疾病中的作用。
Int J Mol Sci. 2018 Nov 9;19(11):3528. doi: 10.3390/ijms19113528.
4
Recent Advances in CNS P2X7 Physiology and Pharmacology: Focus on Neuropsychiatric Disorders.中枢神经系统P2X7生理学与药理学的最新进展：聚焦神经精神疾病
Front Pharmacol. 2018 Feb 1;9:30. doi: 10.3389/fphar.2018.00030. eCollection 2018.
From C-Reactive Protein to Interleukin-6 to Interleukin-1: Moving Upstream To Identify Novel Targets for Atheroprotection.
从C反应蛋白到白细胞介素-6再到白细胞介素-1：向上游探索以确定动脉粥样硬化保护的新靶点。
Circ Res. 2016 Jan 8;118(1):145-56. doi: 10.1161/CIRCRESAHA.115.306656.
4
Association of serum interleukin 6 and C-reactive protein in childhood with depression and psychosis in young adult life: a population-based longitudinal study.血清白细胞介素 6 和 C 反应蛋白与儿童期抑郁症和成年早期精神病的关系：一项基于人群的纵向研究。
JAMA Psychiatry. 2014 Oct;71(10):1121-8. doi: 10.1001/jamapsychiatry.2014.1332.
5
Tumor necrosis factor and its targets in the inflammatory cytokine pathway are identified as putative transcriptomic biomarkers for escitalopram response.肿瘤坏死因子及其在炎症细胞因子途径中的靶点被确定为依他普仑反应的潜在转录组生物标志物。
Eur Neuropsychopharmacol. 2013 Sep;23(9):1105-14. doi: 10.1016/j.euroneuro.2012.09.009. Epub 2012 Nov 9.
6
A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers.一项针对肿瘤坏死因子拮抗剂英夫利昔单抗治疗抵抗性抑郁症的随机对照试验：基线炎症生物标志物的作用。
JAMA Psychiatry. 2013 Jan;70(1):31-41. doi: 10.1001/2013.jamapsychiatry.4.
7
Association of high-sensitivity C-reactive protein with de novo major depression.高敏 C 反应蛋白与首发重大抑郁症的相关性。
Br J Psychiatry. 2010 Nov;197(5):372-7. doi: 10.1192/bjp.bp.109.076430.
8
A meta-analysis of cytokines in major depression.抑郁症中细胞因子的荟萃分析。
Biol Psychiatry. 2010 Mar 1;67(5):446-57. doi: 10.1016/j.biopsych.2009.09.033. Epub 2009 Dec 16.
9
The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters.促炎细胞因子白细胞介素-1β和肿瘤坏死因子-α可激活5-羟色胺转运体。
Neuropsychopharmacology. 2006 Oct;31(10):2121-31. doi: 10.1038/sj.npp.1301029. Epub 2006 Feb 1.
10
Endogenous interleukin-10 is required for the defervescence of fever evoked by local lipopolysaccharide-induced and Staphylococcus aureus-induced inflammation in rats.内源性白细胞介素-10是大鼠局部脂多糖诱导和金黄色葡萄球菌诱导的炎症所引起发热消退所必需的。
J Physiol. 2003 Jun 1;549(Pt 2):653-64. doi: 10.1113/jphysiol.2002.037291. Epub 2003 Apr 11.