Department of Dermatology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA; Department of Dermatology, VA NY Harbor Health Care System, 800 Poly Place, Brooklyn, NY 11209, USA; Department of Dermatology, Mount Sinai Medical Center, 5 East 98th Street, New York, NY 10029, USA.
Department of Dermatology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA; Department of Dermatology, VA NY Harbor Health Care System, 800 Poly Place, Brooklyn, NY 11209, USA; Department of Dermatology, Mount Sinai Medical Center, 5 East 98th Street, New York, NY 10029, USA.
Dermatol Clin. 2017 Oct;35(4):465-488. doi: 10.1016/j.det.2017.06.008. Epub 2017 Aug 9.
Optical coherence tomography (OCT) has emerged as a novel noninvasive imaging device that allows for the real-time, in vivo, cross-sectional imaging of skin morphology. OCT has increased imaging depth and field of view compared with reflectance confocal microscopy, at the cost of decreased cellular resolution. Frequency domain OCT, dynamic OCT (D-OCT), and high-definition OCT (HD-OCT) are useful in the diagnosis, treatment planning, and treatment monitoring of nonmelanoma skin cancers. Research is currently underway to assess the utilization of these devices in distinguishing between malignant and benign melanocytic lesions based on vascular patterns on D-OCT and cellular information on HD-OCT.
光学相干断层扫描（OCT）已成为一种新型的非侵入性成像设备，可实时、在体对皮肤形态进行横截面成像。与反射共焦显微镜相比，OCT 增加了成像深度和视野，代价是降低了细胞分辨率。频域 OCT、动态 OCT（D-OCT）和高清 OCT（HD-OCT）可用于诊断、治疗计划和非黑色素瘤皮肤癌的治疗监测。目前正在研究这些设备在基于 D-OCT 的血管模式和 HD-OCT 的细胞信息来区分恶性和良性黑色素瘤病变方面的应用。
