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肥厚性烧伤瘢痕研究：从定量评估到设计临床序贯多重分配随机试验

Hypertrophic Burn Scar Research: From Quantitative Assessment to Designing Clinical Sequential Multiple Assignment Randomized Trials.

作者信息

Diegidio Paul, Hermiz Steven, Hibbard Jonathan, Kosorok Michael, Hultman Charles Scott

机构信息

Division of Plastic Surgery, University of North Carolina at Chapel Hill, Suite 7038, Burnett-Womack, Chapel Hill, NC 27599, USA.

Department of Surgery, University of South Carolina, 2 Medical Park Road, Columbia, SC 29203, USA.

出版信息

Clin Plast Surg. 2017 Oct;44(4):917-924. doi: 10.1016/j.cps.2017.05.024. Epub 2017 Aug 1.

DOI:10.1016/j.cps.2017.05.024
PMID:28888317
Abstract

This article explores the current options for the quantitative assessment of hypertrophic burn scars. It also introduces a novel type of randomized, controlled trial, which relies on heterogeneity of the subject population to improve the predictive value of personalized treatment strategies.

摘要

本文探讨了目前对肥厚性烧伤瘢痕进行定量评估的方法。它还介绍了一种新型的随机对照试验，该试验依赖于受试者群体的异质性来提高个性化治疗策略的预测价值。

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Hypertrophic Burn Scar Research: From Quantitative Assessment to Designing Clinical Sequential Multiple Assignment Randomized Trials.肥厚性烧伤瘢痕研究：从定量评估到设计临床序贯多重分配随机试验
Clin Plast Surg. 2017 Oct;44(4):917-924. doi: 10.1016/j.cps.2017.05.024. Epub 2017 Aug 1.
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Hypertrophic burn scar management: what does the evidence show? A systematic review of randomized controlled trials.肥厚性烧伤瘢痕的管理：证据表明了什么？一项随机对照试验的系统评价
Ann Plast Surg. 2014;72(6):S198-201. doi: 10.1097/SAP.0000000000000103.
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Hypertrophic scar.肥厚性瘢痕
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Prevention and curative management of hypertrophic scar formation.增生性瘢痕形成的预防和治疗管理。
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[Effects of scar excision combined with negative-pressure on repair of hypertrophic scar in burn children].[瘢痕切除联合负压对小儿烧伤增生性瘢痕修复的影响]
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Use of pressure to treat hypertrophic burn scars.使用压力治疗肥厚性烧伤瘢痕。
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[Verapamil in conjunction with pressure therapy in the treatment of pathologic scar due burn injury].维拉帕米联合压力疗法治疗烧伤后病理性瘢痕
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引用本文的文献

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Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway.间充质干细胞来源的外泌体通过 TNFSF-13/HSPG2 信号通路抑制成纤维细胞缓解增生性瘢痕。
Int J Nanomedicine. 2023 Nov 28;18:7047-7063. doi: 10.2147/IJN.S433510. eCollection 2023.
2
Inhibition of ANGPT2 activates autophagy during hypertrophic scar formation via PI3K/AKT/mTOR pathway.ANGPT2 抑制通过 PI3K/AKT/mTOR 通路在肥厚性瘢痕形成过程中激活自噬。
An Bras Dermatol. 2023 Jan-Feb;98(1):26-35. doi: 10.1016/j.abd.2021.12.005. Epub 2022 Oct 19.
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Sample size considerations for comparing dynamic treatment regimens in a sequential multiple-assignment randomized trial with a continuous longitudinal outcome.
在具有连续纵向结果的序贯多分配随机试验中比较动态治疗方案时的样本量考量
Stat Methods Med Res. 2020 Jul;29(7):1891-1912. doi: 10.1177/0962280219877520. Epub 2019 Oct 1.