Unloaded polyisobutylcyanoacrylate nanoparticles: efficiency against bloodstream trypanosomes.
作者信息
Lherm C, Couvreur P, Loiseau P, Bories C, Gayral P
机构信息
Laboratorie de Pharmacie Galénique et de Biopharmacie, Université de Paris XI, Chatenay-Malabry, France.
出版信息
J Pharm Pharmacol. 1987 Aug;39(8):650-2. doi: 10.1111/j.2042-7158.1987.tb03446.x.
Abstract
The potential use of polyisobutylcyanoacrylate nanoparticles in antiparasitic chemotherapy is described. The nanoparticles on their own proved to have trypanocidal activity against Trypanosoma brucei brucei in-vitro but not against Trichomonas vaginalis or Entamoeba histolytica. The trypanocidal activity was partly confirmed in-vivo with T. brucei-infected mice.
摘要
Zotero 插件