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应用IEUBK模型关联中国南方某矿区儿童血铅水平与环境暴露情况

Application of the IEUBK model for linking Children's blood lead with environmental exposure in a mining site, south China.

作者信息

Zhang Xin-Ying, Carpenter David O, Song Yong-Jin, Chen Ping, Qin Yaoming, Wei Ni-Yu, Lin Shan-Chun

机构信息

Key Laboratory of Beibu Gulf Environment Change and Resources Utilization, Guangxi Teachers Education University, Nanning 530001, China; Institue for Health and the Environment, University at Albany, Rensselaer, NY 12144, USA.

Institue for Health and the Environment, University at Albany, Rensselaer, NY 12144, USA.

出版信息

Environ Pollut. 2017 Dec;231(Pt 1):971-978. doi: 10.1016/j.envpol.2017.08.116. Epub 2017 Sep 25.

Abstract

This study consisted of a site- and age-specific investigation linking children's blood lead level (BLL) to environmental exposures in a historic mining site in south China. A total of 151 children, aged 3-7 years, were included in this study. The geometric mean (GM) BLL was 8.22 μg/dl, indicating an elevated BLL. The Integrated Exposure Uptake Bio-Kinetic (IEUBK) model has proven useful at many sites for study of routes of exposure. Application of the IEUBK model to these children indicated that the GM difference between observed and predicted BLL levels was only 1.07 μg/dl. It was found that the key environmental exposure pathway was soil/dust intake, which contributed 86.3% to the total risk. Younger children had higher BLL than did older children. Therefore, of the various low risk-high benefit solutions, interventions for the children living near the site should be focused on the dust removal and soil remediation. Implementation of the China Eco-village Construction Plan and China New Rural Reconstruction Movement of the government may be a better solution.

摘要

本研究对中国南方一个历史悠久的矿区儿童血铅水平(BLL)与环境暴露之间的关系进行了特定地点和年龄的调查。本研究共纳入151名3至7岁的儿童。血铅水平几何均值(GM)为8.22μg/dl,表明血铅水平升高。综合暴露摄取生物动力学(IEUBK)模型已被证明在许多地点对研究暴露途径很有用。将IEUBK模型应用于这些儿童表明,观察到的和预测的血铅水平之间的几何均值差异仅为1.07μg/dl。研究发现,关键的环境暴露途径是土壤/灰尘摄入,其对总风险的贡献率为86.3%。年幼儿童的血铅水平高于年长儿童。因此,在各种低风险高效益的解决方案中,对居住在该地点附近儿童的干预应侧重于除尘和土壤修复。政府实施中国生态村建设计划和中国新农村建设运动可能是一个更好的解决方案。

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