Department of Physical Therapy and Rehabilitation Science, School of Medicine, University of Maryland, Baltimore, MD.
Department of Physical Therapy and Rehabilitation Science, School of Medicine, University of Maryland, Baltimore, MD.
Arch Phys Med Rehabil. 2018 Feb;99(2):411-415. doi: 10.1016/j.apmr.2017.08.468. Epub 2017 Sep 7.
The purpose of this article is 2-fold: first, to inform readers of the link between the loss of motor inhibition during rapid eye movement (REM) sleep dreaming, diagnosed as REM sleep behavior disorder, and the future onset of neurodegenerative disorders, such as Parkinson disease and dementia with Lewy bodies; it has been reported that motor disinhibition during REM sleep often precedes the onset of these disorders by years or even decades; second, to consider that the identification of REM sleep behavior disorder and the early involvement of rehabilitation and/or development of home exercise plans may aid in prolonging and even increasing function, independence, and quality of life, should such neurodegenerative disorders develop later in life.
第一,告知读者 REM 睡眠做梦期间运动抑制丧失(即 REM 睡眠行为障碍)与未来神经退行性疾病(如帕金森病和路易体痴呆)发病之间的联系;据报道,REM 睡眠期间的运动障碍常常在这些疾病发病前数年甚至数十年就出现;第二,考虑到 REM 睡眠行为障碍的识别以及早期康复和/或家庭运动计划的介入,可能有助于延长甚至增加功能、独立性和生活质量,即使以后患上神经退行性疾病也是如此。