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本文引用的文献

1
Long-Term Outcome of the Sorin Freedom SOLO Stentless Aortic Valve.索林自由SOLO无支架主动脉瓣的长期结果
J Heart Valve Dis. 2016 Nov;25(6):679-684.
2
Clinical outcome and hemodynamic behavior of the Labcor Dokimos Plus aortic valve.Labcor Dokimos Plus主动脉瓣的临床结果和血流动力学表现
J Cardiothorac Surg. 2016 Nov 29;11(1):160. doi: 10.1186/s13019-016-0561-5.
3
Mid-term haemodynamic and clinical results after aortic valve replacement using the Freedom Solo stentless bioprosthesis versus the Carpentier Edwards Perimount stented bioprosthesis.
Eur J Cardiothorac Surg. 2016 Apr;49(4):1174-80. doi: 10.1093/ejcts/ezv255. Epub 2015 Jul 29.
4
The St Jude Medical Trifecta aortic pericardial valve: results from a global, multicenter, prospective clinical study.圣犹达医疗三尖瓣主动脉心包瓣:一项全球性、多中心、前瞻性临床研究结果。
J Thorac Cardiovasc Surg. 2014 Feb;147(2):590-7. doi: 10.1016/j.jtcvs.2012.12.087. Epub 2013 Mar 7.
5
Thrombocytopenia following implantation of the stentless biological sorin freedom SOLO valve.植入无支架生物索林自由SOLO瓣膜后出现血小板减少症。
J Heart Valve Dis. 2011 Jul;20(4):401-6.
6
The Freedom SOLO valve for aortic valve replacement: clinical and hemodynamic results from a prospective multicenter trial.用于主动脉瓣置换的Freedom SOLO瓣膜:一项前瞻性多中心试验的临床和血流动力学结果
J Heart Valve Dis. 2010 Jan;19(1):115-23.
7
Thrombocytopenia after aortic valve replacement with the Freedom Solo stentless bioprosthesis.使用Freedom Solo无支架生物瓣膜进行主动脉瓣置换术后的血小板减少症。
Interact Cardiovasc Thorac Surg. 2008 Aug;7(4):616-20. doi: 10.1510/icvts.2007.169326. Epub 2008 May 27.
8
Stentless versus conventional xenograft aortic valve replacement: midterm results of a prospectively randomized trial.无支架与传统异种移植主动脉瓣置换术:一项前瞻性随机试验的中期结果
Ann Thorac Surg. 2007 Aug;84(2):467-72. doi: 10.1016/j.athoracsur.2007.02.017.
9
Meta-analysis of valve hemodynamics and left ventricular mass regression for stentless versus stented aortic valves.无支架与有支架主动脉瓣膜的瓣膜血流动力学及左心室质量回归的荟萃分析。
Ann Thorac Surg. 2007 Jul;84(1):73-8. doi: 10.1016/j.athoracsur.2007.02.057.
10
Carpentier-Edwards Perimount Magna valve versus Medtronic Hancock II: a matched hemodynamic comparison.卡朋蒂埃-爱德华兹卓越 Magna 瓣膜与美敦力汉考克 II 型瓣膜:配对血流动力学比较
Ann Thorac Surg. 2007 Jun;83(6):2054-8. doi: 10.1016/j.athoracsur.2007.02.062.

心包主动脉瓣的血流动力学:当代带支架瓣膜与无支架瓣膜的匹配比较

Hemodynamics of Pericardial Aortic Valves: Contemporary Stented versus Stentless Valves in a Matched Comparison.

作者信息

Christ Torsten, Holinski Sebastian, Zhigalov Konstantin, Zielinski Christina Barbara, Grubitzsch Herko

机构信息

Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Cardiovascular Surgery, Berlin, Germany.

出版信息

Ann Thorac Cardiovasc Surg. 2017 Dec 20;23(6):298-303. doi: 10.5761/atcs.oa.17-00061. Epub 2017 Sep 8.

DOI:10.5761/atcs.oa.17-00061
PMID:28890465
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5738451/
Abstract

PURPOSE

Hemodynamic performance of aortic valve bioprostheses is essential for reliable function and durability. So far, the supra-annularly implanted stentless Sorin Freedom Solo (SFS) demonstrated unsurpassed hemodynamic properties. As contemporary stented and externally mounted pericardial bioprostheses, like the Labcor Dokimos Plus (LDP), also improve hemodynamic performance, these types of valves were compared in this study.

METHODS

A total of 218 patients, who underwent aortic valve replacement with the LDP or the SFS, were matched retrospectively 1:1 on variables affecting hemodynamic measurements: implanted valve size, age, sex, and body surface area (BSA). With matching tolerance for valve size and gender of 0%, for age and BSA of 5%, 57 patient-pairs were yielded. Operative data, clinical, and hemodynamic outcome were analyzed.

RESULTS

Except for slightly higher left ventricular function and lower procedural times in the SFS group, preoperative, operative, and postoperative characteristics of patient-pairs did not differ significantly. Mean pressure gradients, effective orifice areas (EOAs), and indexed EOAs were comparable. Corresponding to valve sizes of 21, 23, 25, and 27 mm, the indexed EOAs of the LDP and SFS prostheses were 1.08 ± 0.33, 0.92 ± 0.19, 0.93 ± 0.24, 0.99 ± 0.13 cm/m and 0.81 ± 0.13, 0.92 ± 0.28, 0.95 ± 0.20, 1.04 ± 0.27 cm/m, respectively.

CONCLUSION

Contemporary stented and stentless pericardial bioprostheses showed excellent hemodynamic properties without significant differences in EOAs and indexed EOAs.

摘要

目的

主动脉瓣生物假体的血流动力学性能对于可靠的功能和耐久性至关重要。到目前为止,瓣环上植入的无支架索林自由单瓣(SFS)展现出了无与伦比的血流动力学特性。由于当代有支架和外部安装的心包生物假体,如Labcor Dokimos Plus(LDP),也能改善血流动力学性能,本研究对这些类型的瓣膜进行了比较。

方法

共有218例行LDP或SFS主动脉瓣置换术的患者,根据影响血流动力学测量的变量进行回顾性1:1匹配:植入瓣膜大小、年龄、性别和体表面积(BSA)。瓣膜大小和性别的匹配公差为0%,年龄和BSA的匹配公差为5%,得到57对患者。分析手术数据、临床和血流动力学结果。

结果

除SFS组左心室功能略高和手术时间较短外,配对患者的术前、术中和术后特征无显著差异。平均压力阶差、有效瓣口面积(EOA)和指数化EOA相当。对应于21、23、25和27mm的瓣膜大小,LDP和SFS假体的指数化EOA分别为1.08±0.33、0.92±0.19、0.93±0.24、0.99±0.13cm/m²和0.81±0.13、0.92±0.28、0.95±0.20、1.04±0.27cm/m²。

结论

当代有支架和无支架心包生物假体均显示出优异的血流动力学特性,EOA和指数化EOA无显著差异。