Zhan Yi, Buckey Jay C, Fellows Abigail M, Shi Yuxin
Department of Radiology, Shanghai Public Health Clinic Center, Fudan University, Shanghai, China.
Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
J AIDS Clin Res. 2017 Jul;8(7). doi: 10.4172/2155-6113.1000708. Epub 2017 Jul 11.
New research suggests that individuals with human immunodeficiency virus (HIV) have central auditory processing deficits. To review the evidence for HIV affecting parts of the central nervous system involved in central auditory processing, we performed a systematic review of the literature. The objective was to determine whether existing studies show evidence for damage to structures associated with central auditory pathways in HIV. We searched PubMed for papers that used structural magnetic resonance imaging (MRI), diffusion tensor imaging, magnetic resonance spectroscopy or functional MRI in individuals infected with HIV. The review showed that HIV affects several areas involved in central auditory processing particularly the thalamus, internal capsule and temporal cortex. These findings support the idea that HIV can affect central auditory pathways and support the potential use of central auditory tests as a way to assess central nervous system effects of HIV.
新研究表明，感染人类免疫缺陷病毒（HIV）的个体存在中枢听觉处理缺陷。为了回顾HIV影响参与中枢听觉处理的中枢神经系统部分的证据，我们对文献进行了系统综述。目的是确定现有研究是否显示出HIV对与中枢听觉通路相关结构造成损害的证据。我们在PubMed上搜索了在感染HIV的个体中使用结构磁共振成像（MRI）、扩散张量成像、磁共振波谱或功能MRI的论文。综述表明，HIV会影响参与中枢听觉处理的几个区域，尤其是丘脑、内囊和颞叶皮质。这些发现支持了HIV可影响中枢听觉通路的观点，并支持将中枢听觉测试作为评估HIV对中枢神经系统影响的一种潜在方法。
