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TS-1 单药治疗作为晚期外阴 Paget 病二线治疗的成功案例:两例报告。

Successful TS-1 monotherapy as the second-line treatment for advanced extramammary Paget's disease: A report of two cases.

机构信息

Department of Dermatology, Sapporo Medical University School of Medicine, Sapporo, Japan.

出版信息

J Dermatol. 2018 Jan;45(1):80-82. doi: 10.1111/1346-8138.14017. Epub 2017 Sep 11.

Abstract

There is no standard chemotherapeutic treatment for advanced extramammary Paget's disease, though the effectiveness of some chemotherapy regimens, including docetaxel, has been reported. In this report, we report that TS-1 monotherapy was effective in two patients with advanced extramammary Paget's disease after docetaxel treatment failure. TS-1 monotherapy may be useful as the second-line treatment for patients with advanced extramammary Paget's disease.

摘要

对于晚期外阴 Paget 病,目前尚无标准的化疗治疗方法,尽管一些化疗方案(包括多西紫杉醇)的疗效已被报道。在本报告中,我们报告了在多西紫杉醇治疗失败后,TS-1 单药治疗对两名晚期外阴 Paget 病患者有效。TS-1 单药治疗可能对晚期外阴 Paget 病患者作为二线治疗有用。

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