Mauro C, Sperlongano P
Università degli Studi di Napoli, I Facoltà di Medicina e Chirurgia, II Clinica Chirurgica Generale e Terapia Chirurgica.
Minerva Med. 1987 Sep 30;78(18):1381-4.
In order to study the efficacy of estazolam versus triazolam in preoperative patients, two groups of 49 patients each were treated with 2 mg estazolam and 0.5 mg triazolam in a single dose, the night before surgery. This controlled study was designed to evaluate sleep patterns, emotional status on awakening and side effects, by the administration of a questionnaire either in the morning of the day before (baseline) or on the morning of surgery. The results show better sleep patterns after estazolam excepting the duration of sleep that was the same for the two drugs. The better emotional status upon awakening in the morning before surgery and the lower incidence of side effects in the patients treated with estazolam, lead to the conclusion that estazolam is clearly better than triazolam in the treatment of preoperative patients.
为研究艾司唑仑与三唑仑对术前患者的疗效，两组各49例患者于手术前一晚单次服用2毫克艾司唑仑和0.5毫克三唑仑。这项对照研究旨在通过在手术前一天上午（基线）或手术当天上午发放问卷，评估睡眠模式、醒来时的情绪状态和副作用。结果显示，除睡眠时间两种药物相同外，艾司唑仑治疗后的睡眠模式更佳。术前早晨醒来时情绪状态更好，且服用艾司唑仑的患者副作用发生率更低，由此得出结论，在治疗术前患者方面，艾司唑仑明显优于三唑仑。
