Durand J, Engberg I, Tyc-Dumont S
C.N.R.S. UA634, INSERM U6, Marseille, France.
Neurosci Lett. 1987 Aug 31;79(3):295-300. doi: 10.1016/0304-3940(87)90447-2.
The actions of L-glutamate and N-methyl-D-aspartate (NMDA) were studied with intracellular recordings from cat abducens motoneurones. Amino acids were electrophoresed extracellularly from the same 7-barreled electrode types as those used in the spinal cord. Depolarization development, conductance changes and firing pattern induced by amino acids were very similar to those described for spinal motoneurones. The shape of NMDA depolarization suggests a uniform distribution of the involved receptors on the membrane of the motoneurone.
利用猫展神经运动神经元的细胞内记录，研究了L-谷氨酸和N-甲基-D-天冬氨酸（NMDA）的作用。氨基酸从与脊髓实验中使用的相同类型的七管电极进行细胞外电泳。氨基酸诱导的去极化发展、电导变化和放电模式与脊髓运动神经元所描述的非常相似。NMDA去极化的形状表明相关受体在运动神经元膜上呈均匀分布。
