Lelbovitz A, Wright W C, Pathak S, Siciliano M J, Daniels W P
J Natl Cancer Inst. 1979 Sep;63(3):635-45. doi: 10.1093/jnci/63.3.635.
Eight of approximately 100 cell lines derived at the Scott and White Clinic from human solid tumors were found to have the same phenotypes when analyzed for 15 polymorphic enzymes at the Sloan-Kettering Institute for Cancer Research. These data were confirmed at the M. D. Anderson Hospital and Tumor Institute. The similarity was supported by cytogenetic studies at both institutions. The chronology of the establishment of these cell lines and isoenzyme and cytogenetic studies indicated that six of these lines have cross cell contamination. These include SW-527 and SW-613 mammary carcinomas, SW-598 meningioma, SW-608 astrocytoma, SW-732 cervix carcinoma, and SW-733 bladder carcinoma. Our data supported the authenticity of SW-480 and SW-620, which were derived from a colon carcinoma and its metastasis, respectively, from the same patient.
在斯科特与怀特诊所从人类实体瘤中提取的约100个细胞系中，有8个在斯隆 - 凯特琳癌症研究所接受15种多态酶分析时表现出相同的表型。这些数据在MD安德森医院和肿瘤研究所得到了证实。两个机构的细胞遗传学研究都支持了这种相似性。这些细胞系的建立时间顺序以及同工酶和细胞遗传学研究表明，其中6个细胞系存在交叉污染。这些包括SW - 527和SW - 613乳腺癌、SW - 598脑膜瘤、SW - 608星形细胞瘤、SW - 732宫颈癌和SW - 733膀胱癌。我们的数据支持了SW - 480和SW - 620的真实性，它们分别来自同一患者的结肠癌及其转移瘤。
