Markovic O, Markovic N
BioSciCon, Inc., Rockville, MD 20852, USA.
In Vitro Cell Dev Biol Anim. 1998 Jan;34(1):1-8. doi: 10.1007/s11626-998-0040-y.
Cell cross-contamination in cell cultures is a common problem during cell culturing and use. Contamination invalidates research results, compromises the comparison of results between laboratories, reduces reproducibility required in industrial production of cell lines, and may lead to unusable therapeutic products. The problem can be solved by increasing the awareness of its seriousness and by introducing regular quality control of cell cross-contamination in every laboratory where cells are grown and used.
细胞培养中的细胞交叉污染是细胞培养和使用过程中常见的问题。污染会使研究结果无效，影响实验室之间结果的比较，降低细胞系工业生产所需的可重复性，并可能导致治疗产品无法使用。通过提高对其严重性的认识，并在每个培养和使用细胞的实验室引入定期的细胞交叉污染质量控制，可以解决这个问题。
