Salman Hamzah Abdulrahman, Kumar R Senthil, Babu N Chaitanya, Imran Khalid
Research Scholar, Department of Microbiology, J.J. College of Arts and Science, Affiliated to Bharathidasan University, Pudukkottai, Tamil Nadu, India.
Associate Professor, Department of Microbiology, J.J. College of Arts and Science, Affiliated to Bharathidasan University, Pudukkottai, Tamil Nadu, India.
J Clin Diagn Res. 2017 Jul;11(7):DM01-DM03. doi: 10.7860/JCDR/2017/25903.10316. Epub 2017 Jul 1.
Mutans streptococci (MS) are a group of oral bacteria generally regarded as the principal agents in the pathogenesis of dental caries.
The study aimed was characterize based on phylogenetic analysis and phenotypic methods from Caries Active Subject.
While sequencing MS species which were isolated from 65 caries active subjects, one strain of was detected. Dental plaque samples were processed and cultured on mitis salivarius bacitracin agar. was characterized using phylogenetic analysis, colony morphology characterization and biotyping.
Among the study population, one strain designated as H14 was identified as by 16S rDNA sequencing. Morphologically, could not differentiate from other species of MS. H14 demonstrated biotype II biochemical characteristics of MS. The phylogenetic analysis showed is closely related to .
The study concludes that can inhabit the human oral cavity and therefore further investigations are warranted to determine its role in caries.
变形链球菌（MS）是一组口腔细菌，通常被认为是龋齿发病机制中的主要致病菌。
本研究旨在基于系统发育分析和表型方法对龋活跃受试者进行特征描述。
在对从65名龋活跃受试者中分离出的变形链球菌进行测序时，检测到一株[未提及具体菌株名称]。对牙菌斑样本进行处理，并在轻唾链球杆菌血平板上培养。通过系统发育分析、菌落形态特征描述和生物分型对[未提及具体菌株名称]进行特征描述。
在研究人群中，一株命名为H14的菌株经16S rDNA测序鉴定为[未提及具体菌株名称]。在形态上，[未提及具体菌株名称]无法与其他变形链球菌物种区分开来。H14表现出变形链球菌的II型生化特征。系统发育分析表明[未提及具体菌株名称]与[未提及具体相关菌株名称]密切相关。
该研究得出结论，[未提及具体菌株名称]可寄居于人类口腔，因此有必要进一步研究以确定其在龋齿中的作用。
