Amita Krishnappa, Govind Abhishek Mandya, Pechiat Tony, Manchaih Sanjay, Shankar Shivshankar Vijay
Associate Professor, Department of Pathology, Adichunchanagiri Institute of Medical Sciences, BG Nagara, Mandya, Karnataka, India.
Post graduate, Department of Pathology, Adichunchanagiri Institute of Medical Sciences, BG Nagara, Mandya, Karnataka, India.
J Clin Diagn Res. 2017 Jul;11(7):ED18-ED20. doi: 10.7860/JCDR/2017/26062.10227. Epub 2017 Jul 1.
A 60-year-old male, diabetic presented with a soft tissue mass over the right forearm of 15 days duration. The swelling was 5 x 3 cm and a clinical diagnosis of neurofibroma was made. Fine Needle Aspiration Cytology (FNAC) was done using standard technique. Smears showed predominantly suppurative inflammation, foreign body giant cells, granulomas and fungal hyphae. KOH mount, culture and germ tube test was positive. Final diagnosis of fungal granuloma was made. Fungal infections should be included in the differential diagnosis of a soft tissue mass lesion. All soft tissue suppurative inflammatory lesions should be diligently screened to look for pathogens if any. Diagnostics in medicine have taken a major leap with advent of molecular technologies. Despite this, simple old traditional methods like FNAC supplemented by other basic laboratory techniques like KOH mount and culture still form the cream of a diagnostic laboratory and can come as a savior for the pathologist, the clinicians and the patients.
一名60岁男性糖尿病患者,右前臂出现持续15天的软组织肿块。肿块大小为5×3厘米,临床诊断为神经纤维瘤。采用标准技术进行了细针穿刺细胞学检查(FNAC)。涂片显示主要为化脓性炎症、异物巨细胞、肉芽肿和真菌菌丝。氢氧化钾涂片、培养及芽管试验呈阳性。最终诊断为真菌性肉芽肿。真菌感染应列入软组织肿块病变的鉴别诊断。所有软组织化脓性炎性病变都应仔细筛查以寻找病原体(如有)。随着分子技术的出现,医学诊断有了重大飞跃。尽管如此,像FNAC这样简单的传统方法辅以氢氧化钾涂片和培养等其他基本实验室技术,仍然是诊断实验室的核心方法,对病理学家、临床医生和患者来说可能是救星。