Jhingan Ashok, Jhingan Ram Mohan
Chairman and Consultant, Department of Diabetology, Delhi Diabetes Education and Research Foundation, New Delhi, India.
Fellow, Department of Endrocrinology, Einstein Medical Centre, Philadelphia, Pennsylvania, United States.
J Clin Diagn Res. 2017 Jul;11(7):OC09-OC11. doi: 10.7860/JCDR/2017/28111.10162. Epub 2017 Jul 1.
Aerobic exercise is associated with significant improvement in glycaemia and weight loss in Type 2 diabetes (T2D). Cycling, a form of aerobic exercise can benefit young (18 to <40 years) individuals with T2D.
To assess effect of cycling on glycosylated haemoglobin (HbA1c), blood pressure (BP) and weight over six months in young individuals with T2D.
In this retrospective, observational study, young (18 to <40 years) T2D patients who were being treated without insulin and not on more than two Oral Antidiabetic Drugs (OADs) were identified from a group of cyclists in a metro city from Northern India. These individuals were involved in a regular exercise program (cycling 25 km/day for at least five days a week). Participants with consecutive six months of cycling were selected and those involved in other forms of exercise were excluded. From their medical records, participants' weight, BP, and HbA1c levels were noted at baseline (i.e., before the start) and post-six months of cycling program and evaluated with appropriate statistics.
From 26 cases identified with T2D, 20 participants were included in analysis. Mean age of participants was 35.6±2.6 years, five were <35 years and all of them were males. Cycling resulted in significant reduction in HbA1c% (mean change from baseline at six-month: -1.18, 95% Confidence Interval (CI) 1.12, 1.24; p<0.001). Besides, systolic (-5.2, 95% CI -3.7, -6.6; p<0.001) and diastolic (-3.1, 95% CI -1.7, -4.5; p<0.001) BP and weight (kg) (-5.0, 95% CI -4.41, -5.58; p<0.001) showed significant reduction from baseline to six-months. Among two age groups (Age < 35 and ≥ 35 years), except for reduction of diastolic BP in age < 35 years, significant reduction in all other parameters was evident in both age groups.
Regular aerobic exercise in cycling form results in significant reduction in HbA1c, BP and weight. It should be promoted as an ideal method for exercise in young T2D cases to derive maximum benefits and to improve adherence to lifestyle intervention.
有氧运动与2型糖尿病（T2D）患者的血糖显著改善和体重减轻有关。骑自行车作为有氧运动的一种形式，对年轻（18至<40岁）的T2D患者有益。
评估骑自行车对年轻T2D患者六个月内糖化血红蛋白（HbA1c）、血压（BP）和体重的影响。
在这项回顾性观察研究中，从印度北部一个大城市的一群骑自行车的人中，识别出年龄在18至<40岁之间、未使用胰岛素治疗且口服抗糖尿病药物（OADs）不超过两种的T2D患者。这些人参与了一项常规运动计划（每周至少五天，每天骑行25公里）。选择连续骑行六个月的参与者，并排除参与其他运动形式的人。从他们的病历中，记录参与者在基线（即开始前）和骑行计划六个月后的体重、血压和HbA1c水平，并进行适当的统计评估。
从26例确诊为T2D的病例中，20名参与者纳入分析。参与者的平均年龄为35.6±2.6岁，5名年龄<35岁，均为男性。骑行导致HbA1c%显著降低（六个月时相对于基线的平均变化：-1.18，95%置信区间（CI）1.12，1.24；p<0.001）。此外，收缩压（-5.2，95%CI -3.7，-6.6；p<0.001）和舒张压（-3.1，95%CI -1.7，-4.5；p<0.001）以及体重（kg）（-5.0，95%CI -4.41，-5.58；p<0.001）从基线到六个月均显著降低。在两个年龄组（年龄<35岁和≥35岁）中，除了年龄<35岁组的舒张压降低外，两个年龄组的所有其他参数均显著降低。
定期进行骑自行车形式的有氧运动可显著降低HbA1c、血压和体重。应将其作为年轻T2D患者的理想运动方法加以推广，以获得最大益处并提高对生活方式干预的依从性。
