Patil Shankargouda, Rao Roopa S, Raj A Thirumal, Sanketh D S, Sarode Sachin, Sarode Gargi
Associate Professor, Department of Maxillofacial Surgery and Diagnostic Sciences, Division of Oral Pathology, College of Dentistry, Jazan University, Jazan, Saudi Arabia.
Professor and Head, Department of Oral Pathology, Faculty of Dental Sciences, MS Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.
J Clin Diagn Res. 2017 Jul;11(7):ZC22-ZC24. doi: 10.7860/JCDR/2017/27717.10161. Epub 2017 Jul 1.
being a part of the normal oral microbial flora is one of the most commonly isolated species from the oral cavity. Recent studies have shown a steady rise in the number of non species, which are relatively resistant to common antifungal agents and are being recognized as potential pathogens. It is vital to ascertain the predisposing factors leading to such a shift in the oral candidal flora.
To estimate the prevalence of candidal species among vegetarians and non-vegetarians.
Clinical data including age, gender, and diet preference of 238 participants were noted. Participants with a history of systemic disorders, oral prosthesis, salivary gland disorders and habits such as smoking, alcoholism, and tobacco usage were excluded from the study. The participants were asked to gargle a 10 ml solution of phosphate buffered saline for one minute before depositing the same in a sterile container. The samples were cultured using Hicrome agar media. Data analysis was carried out using Statistical Package for Social Sciences (SPSS software) version 10.5 and differences between individual groups were tested by Chi-square test.
Among 238 samples, 127 (53.3%) samples were positive for . The candidal prevalence in vegetarians (68.5%) was higher than non-vegetarians (40.7%). was the most common species to be isolated in both vegetarians (35.1%) and non-vegetarians (39.2%). and showed a higher prevalence in vegetarians (30.5% and 10.1%, respectively) in comparison to non-vegetarians (8.4% and 2.3%, respectively). was isolated only from vegetarians (4.6%).
Results indicate that diet plays a major role in oral candidal prevalence and species specificity which in turn may predispose the vegetarians toward these pathogenic organisms.
作为正常口腔微生物群的一部分，是口腔中最常分离出的物种之一。最近的研究表明，非物种的数量稳步上升，这些物种对常见抗真菌剂具有相对抗性，并被认为是潜在病原体。确定导致口腔念珠菌菌群发生这种转变的诱发因素至关重要。
评估素食者和非素食者中念珠菌物种的患病率。
记录了238名参与者的临床数据，包括年龄、性别和饮食偏好。有全身疾病史、口腔假体、唾液腺疾病以及吸烟、酗酒和使用烟草等习惯的参与者被排除在研究之外。要求参与者用10毫升磷酸盐缓冲盐水溶液漱口一分钟，然后将其放入无菌容器中。样本使用希克罗马琼脂培养基进行培养。使用社会科学统计软件包（SPSS软件）10.5版进行数据分析，通过卡方检验测试各个组之间的差异。
在238个样本中，127个（53.3%）样本的检测结果呈阳性。素食者中的念珠菌患病率（68.5%）高于非素食者（40.7%）。是素食者（35.1%）和非素食者（39.2%）中最常分离出的物种。与非素食者（分别为8.4%和2.3%）相比，和在素食者中的患病率更高（分别为30.5%和10.1%）。仅从素食者中分离出（4.6%）。
结果表明饮食在口腔念珠菌患病率和物种特异性中起主要作用，这反过来可能使素食者更容易感染这些致病生物。
