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确定念珠菌性阴道感染女性中念珠菌属的感染频率 念珠菌性阴道感染女性中念珠菌属的感染频率。

Determining the frequency of Candida species in women with candidal vaginal infection frequency of Candida species in women with candida vaginal infection.

作者信息

Tafazoli Mahin, Gholami Mahboobe, Mohebbi-Dehnavi Zahra, Shaghaghi Fatemeh, Kamali Zahra

机构信息

Department of Midwifery, Evidence-Based Care Research Center, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.

Department of Nursing and Midwifery, Neyshabur University of Medical Sciences, Neyshabur, Iran.

出版信息

J Educ Health Promot. 2021 Dec 31;10:481. doi: 10.4103/jehp.jehp_1334_20. eCollection 2021.

DOI:10.4103/jehp.jehp_1334_20
PMID:35233428
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8826783/
Abstract

BACKGROUND

Candidiasis vaginitis is an opportunistic and common mucosal infection. Although is the most common isolated species, other species of Candida such as , and have also increased significantly in recent years. The aim of this study was to identify species in women with candidal vaginal infection in order to promote health in women.

MATERIALS AND METHODS

This cross-sectional descriptive study was performed on nonpregnant women of childbearing age who referred to health centers in Neyshabur in 2018. At the beginning of the study, 163 people entered the study and the culture results were positive in 68 of them. , culture was performed in subduxtrose agar medium containing chloramphenicol and gentamicin. Species identification was performed using Candida specific culture medium (Saburo dextrose agar and chloramphenicol). After culture, 15% of the residual wet slide with potash (KOH) was prepared and observed with a lens. Finally, the data were analyzed with SPSS software version 24.

RESULTS

The participants in the study were women with a mean age of 35.55 ± 5.47 and the average number of deliveries was 1.38 ± 1.15. In this study, the prevalence of was 59.7%, was 14.8%, was 15%, and was 7.61% and also and were 3% simultaneously. Therefore, was the most common species isolated from clinical specimens.

CONCLUSION

In this study, the most common species after albicans were and cruciferous. Considering the role of in the development of resistance to antifungal drugs, the lower prevalence of this species in the present study can be associated with improved treatment outcomes in patients.

摘要

背景

念珠菌性阴道炎是一种常见的机会性黏膜感染。虽然白色念珠菌是最常分离出的菌种,但近年来其他念珠菌菌种,如光滑念珠菌、热带念珠菌和近平滑念珠菌等也显著增加。本研究的目的是鉴定念珠菌性阴道感染女性中的念珠菌菌种,以促进女性健康。

材料与方法

本横断面描述性研究于2018年对转诊至内沙布尔健康中心的育龄非妊娠女性进行。研究开始时,163人进入研究,其中68人培养结果呈阳性。采用含氯霉素和庆大霉素的沙保弱葡萄糖琼脂培养基进行培养。使用念珠菌特异性培养基(沙氏葡萄糖琼脂和氯霉素)进行菌种鉴定。培养后,制备15%的剩余湿片加氢氧化钾(KOH),并用透镜观察。最后,用SPSS 24版软件对数据进行分析。

结果

研究参与者为平均年龄35.55±5.47岁的女性,平均分娩次数为1.38±1.15次。本研究中,白色念珠菌的患病率为59.7%,光滑念珠菌为14.8%,热带念珠菌为15%,近平滑念珠菌为7.61%,同时季也蒙念珠菌和葡萄牙念珠菌为3%。因此,白色念珠菌是从临床标本中分离出的最常见菌种。

结论

在本研究中,白色念珠菌之后最常见的菌种是光滑念珠菌和热带念珠菌。考虑到光滑念珠菌在抗真菌药物耐药性发展中的作用,本研究中该菌种较低的患病率可能与患者治疗效果改善有关。

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