Keck P E, Pope H G, McElroy S L
Epidemiology Laboratory, McLean Hospital, Belmont, MA 02178.
Am J Psychiatry. 1987 Oct;144(10):1344-6. doi: 10.1176/ajp.144.10.1344.
In an 18-month prospective assessment of 679 hospitalized, neuroleptic-treated patients, the authors, using previously defined operational criteria, diagnosed neuroleptic malignant syndrome in six cases (0.9%). This supports their earlier finding that the syndrome appeared in about 1% of neuroleptic-treated patients.
在一项对679名住院且接受抗精神病药物治疗的患者进行的为期18个月的前瞻性评估中,作者使用先前定义的操作标准,诊断出6例(0.9%)抗精神病药物恶性综合征。这支持了他们早期的发现,即该综合征在约1%的接受抗精神病药物治疗的患者中出现。