Hayakawa Masanobu, Oda Kazuyuki
Department of Thoracic Surgery, Higashiosaka City Medical Center, Higashiosaka, Japan.
Kyobu Geka. 2017 Sep;70(10):883-886.
A thymoma with pure red cell aplasia (PRCA) is relatively rare. A 71-year-old woman complainted of dizziness and her blood cell count showed a severe anemia. She was diagnosed as PRCA by bone marrow aspiration biopsy, which showed marked decrease in number of erythroblasts. In addition, the chest computed tomography revealed a solid tumor in the anterior mediastinum. She underwent extended thymothymectomy through median sternotomy. The resected specimen was 10.5×9.7 cm in diameter. The pathological diagnosis was type AB thymoma of the World Health Organization classification, and Masaoka stage I. Ciclosporin was started to treat PRCA 3 months after the surgery, and she has been well for about 1 year after surgery without recurrence of thymoma or relapse of anemia.
伴有纯红细胞再生障碍性贫血（PRCA）的胸腺瘤相对罕见。一名71岁女性主诉头晕，血细胞计数显示严重贫血。通过骨髓穿刺活检诊断为PRCA，结果显示成红细胞数量显著减少。此外，胸部计算机断层扫描显示前纵隔有一个实体瘤。她通过正中胸骨切开术接受了扩大胸腺切除术。切除标本直径为10.5×9.7厘米。病理诊断为世界卫生组织分类的AB型胸腺瘤，Masaoka分期为I期。术后3个月开始使用环孢素治疗PRCA，术后约1年情况良好，胸腺瘤未复发，贫血也未复发。
